Escherichia coli strain DP254

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain DP254 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The strain is mesophilic, with an optimal growth temperature of 37°C, which aligns closely with the body temperature of many warm-blooded hosts. This strain is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and Bos taurus, among others. Its biotic relationship is categorized as free-living, indicating its ability to exist independently of a host but also reflects its capacity to inhabit various environments associated with these hosts. Escherichia coli strain DP254 has been implicated in numerous health-related issues, primarily affecting the gastrointestinal and urinary systems of humans and animals. It is known to cause urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The range of health effects underscores its pathogenic nature, particularly in humans, where it can lead to serious complications like septicemia and renal failure. The extensive host range and the strain's ability to cause various diseases suggest its ecological versatility and role in both environmental and clinical settings. This adaptability may facilitate its transmission and persistence in different habitats, highlighting the importance of monitoring such strains in public health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain DP254

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain DP254
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain DP254


Gene Summary

Adenine Count

1296665 bp

Thymine Count

1296901 bp

Guanine Count

1331328 bp

Cytosine Count

1307948 bp

Genome Length

5232842 bp

Protein-coding Genes

5112 genes

Non-Coding Genes

251 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Transcriptional regulatorC4K41_22540Not AvailablePositive4416352 - 441696022359.1
mate family efflux transporter dinfC4K41_22545Not AvailablePositive4416979 - 441835849656.5
csbd family proteinC4K41_22550Not AvailablePositive4418474 - 44186838349.69
transcriptional regulator zurC4K41_22555Not AvailableNegative4418725 - 441924019308.3
Hypothetical proteinC4K41_22560Not AvailablePositive4419763 - 442023617299.8
hypothetical proteinC4K41_22565Not AvailablePositive4420259 - 442080719953.4
Hypothetical proteinC4K41_22570Not AvailableNegative4420841 - 442111310362.5
Putative exonucleaseC4K41_22575Not AvailableNegative4421150 - 442172221090.9
Hypothetical proteinC4K41_22580Not AvailableNegative4421722 - 442228820605.2
Hypothetical proteinC4K41_22585Not AvailableNegative4422285 - 44225399339.2

Displaying genes 11 – 20 of 5363 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4801 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4801 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total