Campylobacter jejuni strain CB313 121

Campylobacter jejuni strain CB313 121 is a Gram-negative bacterium characterized by its spiral shape (spirilla) and microaerophilic oxygen requirement. It is a heterotrophic organism that exists in free-living forms and is capable of forming single cells and chains. This strain has a mesophilic temperature range and an optimal growth temperature of 0°C, which is notable for its adaptability to various environments. The bacterium possesses flagella, contributing to its mobility, although specific mobility characteristics are not detailed. With a single replicon and a double membrane structure, CB313 121 aligns with the typical features of Campylobacter species. This strain has a diverse range of hosts, including Homo sapiens, Gallus gallus (domestic chickens), Bos taurus (cattle), Ovis aries (sheep), members of the Phasianidae family (game birds), Canis lupus familiaris (domestic dogs), and Felis catus (domestic cats). This wide host range is significant as it enhances the bacterium's potential for transmission and impacts on both animal and human health. CB313 121 is associated with several health effects, primarily gastrointestinal disorders such as gastroenteritis and campylobacteriosis. It can lead to severe conditions, including bacteremia and Guillain-Barre syndrome (GBS), a serious neurological disorder. The association of this strain with foodborne illnesses underscores its ecological role as a pathogen that can affect human populations through zoonotic transmission from animals, particularly in food production systems.