Campylobacter jejuni strain CB336 118

Gram-negativeSpirillaNon-motileMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter jejuni strain CB336 118 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and the presence of flagella. This strain is heterotrophic, relying on organic compounds for energy, and exhibits a cell arrangement consisting of singles and chains. It possesses a single replicon and has a double membrane structure, typical of its classification within the Campylobacter genus. This strain is mesophilic, with an optimal growth temperature of 0°C and a temperature range that accommodates mesophilic conditions. It is free-living and has been identified in various habitats, indicating its adaptability to different environments. C. jejuni strain CB336 118 has a significant biotic relationship with multiple hosts, including Homo sapiens (humans), Gallus gallus (domestic chicken), Bos taurus (cattle), Ovis aries (sheep), Phasianidae (pheasants), Canis lupus familiaris (domestic dogs), and Felis catus (domestic cats). This broad host range underscores its ecological versatility and potential for zoonotic transmission. The strain is associated with numerous health effects in humans, including bacteremia, bloodstream infections, urinary tract infections, and various forms of gastroenteritis. Notably, it can lead to acute bacterial enteritis and is implicated in Guillain-Barre syndrome (GBS), a serious neurological disorder. The presence of C. jejuni in both human and animal hosts highlights the importance of monitoring this pathogen, particularly in relation to foodborne infections and public health initiatives aimed at preventing enteric diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter jejuni
Strainstrain CB336 118

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Campylobacter jejuni strain CB336 118
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperature0
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementChains - Singles
SporulationNot Available
Energy sourceHeterotroph
Pathogenicitychickens

Genome Summary

Campylobacter jejuni strain CB336 118, whole genome shotgun

Gene Summary

Adenine Count

643562 bp

Thymine Count

651565 bp

Guanine Count

278542 bp

Cytosine Count

278045 bp

Genome Length

1851714 bp

Protein-coding Genes

1897 genes

Non-Coding Genes

46 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sulfate adenylyltransferaseC3H69_04695Not AvailableNegative887911 - 88907144477.9
response regulatorC3H69_04700Not AvailableNegative889049 - 88993634271.4
bifunctional 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase/2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseC3H69_04705Not AvailableNegative889933 - 89104841646.4
iron-sulfur cluster carrier protein apbcC3H69_04710Not AvailablePositive891171 - 89227740137.9
2,3,4,5-tetrahydropyridine-2,6-carboxylate n-succinyltransferaseC3H69_04715Not AvailablePositive892303 - 89346342377.4
bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp diphosphatase hisieC3H69_04720Not AvailableNegative893487 - 89411023242.1
imidazole glycerol phosphate synthase subunit hisfC3H69_04725Not AvailableNegative894112 - 89487928033.8
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomeraseC3H69_04730Not AvailableNegative894861 - 89559526802.1
imidazole glycerol phosphate synthase subunit hishC3H69_04735Not AvailableNegative895592 - 89617921981.5
site-specific dna-methyltransferaseC3H69_04740Not AvailableNegative896176 - 89725541948.4

Displaying genes 911 – 920 of 1943 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Intestinal illnessCausesPMC10942002
Diarrheal illnessCausesPMC10942002
Intestinal campylobacteriosisCausesPMC10942002
Intestinal diseaseCausesPMC10942002
Febrile illnessCausesPMC10942002
Bacterial gastrointestinal infectionsCausesPMC11434686
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289

Displaying health effects 1 – 10 of 36 in total