Campylobacter jejuni strain CB367 76

Gram-negativeSpirillaNon-motileMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter jejuni strain CB367 76 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella. It typically exists in multiple habitats and is a free-living heterotroph, utilizing organic compounds for energy. This strain is mesophilic, with an optimal temperature of 0°C and a single replicon, indicating a streamlined genetic structure. C. jejuni strain CB367 76 is known to infect various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), Bos (bovine), Ovis aries (sheep), members of the Phasianidae family (game birds), Canis lupus familiaris (dogs), and Felis catus (cats). This diverse host range underscores the bacterium's ecological versatility and potential for transmission across species. Clinically, C. jejuni strain CB367 76 is associated with a range of health effects in humans, primarily gastrointestinal diseases. It is implicated in conditions such as bacteremia, bloodstream infections, urinary tract infections, gastroenteritis, and intestinal campylobacteriosis. The strain contributes to diarrheal illnesses, enteric infections, and more severe complications like Guillain-Barre syndrome (GBS). The bacterium’s presence in food sources highlights its role in foodborne gastroenteritis, making it a significant concern for public health. The diverse host range and associated health effects of Campylobacter jejuni strain CB367 76 indicate its importance in both ecological dynamics and human health, particularly in the context of zoonotic transmission and food safety.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter jejuni
Strainstrain CB367 76

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Campylobacter jejuni strain CB367 76
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperature0
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementChains - Singles
SporulationNot Available
Energy sourceHeterotroph
Pathogenicitychickens

Genome Summary

Campylobacter jejuni strain CB367 76, whole genome shotgun

Gene Summary

Adenine Count

648976 bp

Thymine Count

644612 bp

Guanine Count

281637 bp

Cytosine Count

274321 bp

Genome Length

1849546 bp

Protein-coding Genes

1845 genes

Non-Coding Genes

47 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-acetylmuramoyl-l-alanine amidaseC3H94_00145Not AvailablePositive26279 - 2825874689.5
bifunctional trna (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase mnmd/fad-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase mnmcC3H94_00150Not AvailablePositive28255 - 3009671612.1
ni/fe hydrogenaseC3H94_00155Not AvailablePositive30216 - 3135541392.4
hydrogenase 2 large subunitC3H94_00160Not AvailablePositive31358 - 3307363642.0
ni/fe-hydrogenase, b-type cytochrome subunitC3H94_00165Not AvailablePositive33084 - 3377626832.6
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive33090 - 33187Not Available
hydrogenase expression/formation proteinC3H94_00170Not AvailablePositive33773 - 3430920213.6
recombination protein recrC3H94_00175Not AvailableNegative34306 - 3487821514.1
sensor histidine kinaseC3H94_00180Not AvailableNegative34878 - 3611347960.2
dna-binding response regulatorC3H94_00185Not AvailableNegative36110 - 3678125355.7

Displaying genes 31 – 40 of 1892 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Intestinal illnessCausesPMC10942002
Diarrheal illnessCausesPMC10942002
Intestinal campylobacteriosisCausesPMC10942002
Intestinal diseaseCausesPMC10942002
Febrile illnessCausesPMC10942002
Bacterial gastrointestinal infectionsCausesPMC11434686
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289

Displaying health effects 1 – 10 of 36 in total