Campylobacter jejuni strain CB375

Campylobacter jejuni strain CB375 is a Gram-negative microaerophilic bacterium characterized by its spirilla shape and presence of flagella, which facilitate motility. This strain is heterotrophic, utilizing organic compounds for energy, and is typically found in various habitats, reflecting its adaptability. It thrives optimally at ambient temperatures, fitting within a mesophilic temperature range. CB375 exhibits a unique cell arrangement, predominantly existing as singles or in chains, and possesses a single replicon along with a double membrane structure. This bacterium is free-living and has a wide range of hosts, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus), cattle (Bos taurus), sheep (Ovis aries), as well as various species in the Phasianidae family and domestic pets like dogs (Canis lupus familiaris) and cats (Felis catus). Clinically, Campylobacter jejuni strain CB375 is significant due to its association with numerous health effects. It is implicated in various infections such as bacteremia, bloodstream infections, urinary tract infections, and gastroenteritis. It can lead to intestinal campylobacteriosis, resulting in diarrheal illnesses, enteric diseases, and more severe outcomes like Guillain-Barre syndrome (GBS) and septic shock. The presence of this strain in multiple animal hosts highlights its potential as a foodborne pathogen, emphasizing the importance of monitoring and controlling Campylobacter jejuni in food safety practices to prevent enteric diseases in humans.