Escherichia coli strain 286A 286ANODE_120_length_352_cov_40.3022

Escherichia coli strain 286A (286ANODE_120_length_352_cov_40.3022) is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. It is capable of existing in both aerobic and anaerobic environments, which contributes to its adaptability and survival in various habitats, primarily associated with hosts. This strain exhibits mobility, facilitated by the presence of flagella, and is typically found in pairs or singles. The optimal growth temperature for E. coli 286A is 37°C, positioning it within the mesophilic temperature range, which is conducive to its proliferation in warm-blooded hosts. It possesses a single replicon and a double membrane structure typical of Gram-negative bacteria. Its biotic relationship is deemed free-living, although it also shows associations with a wide range of hosts, including various mammalian species (e.g., Homo sapiens, Bos taurus, and Canis lupus familiaris) as well as non-mammalian hosts like Solanum lycopersicum and Apis mellifera. This strain is of significant clinical importance due to its association with numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, septicemia, and neonatal meningitis, among others. The diverse pathogenicity of E. coli 286A underscores its role in human health, as it is linked with various diseases ranging from mild gastrointestinal disturbances to severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The strain's ability to infect multiple hosts suggests a complex ecological role, indicating its adaptability and potential impact on public health, particularly in relation to foodborne infections and zoonotic diseases.