Actinomyces naeslundii strain UMB0181

Gram-positiveFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Actinomyces

Description

Actinomyces naeslundii strain UMB0181 is a Gram-positive bacterium characterized as a facultative anaerobe. This strain is primarily found in the submucosal sulcus of the human host, Homo sapiens. It has a single replicon, which is indicative of its genomic structure. This bacterium is associated with several health effects, notably dental caries and actinomycosis. Dental caries, commonly known as tooth decay, highlights the role of A. naeslundii in oral microbiology and its potential contribution to the pathogenicity of dental diseases. Actinomycosis, a chronic bacterial infection, further emphasizes its clinical significance. The accessions for this strain are cataloged under PKKP00000000.1, providing a reference for researchers interested in studying its genetic and phenotypic characteristics. In terms of ecological insight, A. naeslundii's ability to thrive in the submucosal sulcus suggests its adaptation to a niche that supports both its survival and potential pathogenicity. This ecological role underscores the importance of understanding microbial communities in the oral cavity, as organisms like A. naeslundii contribute to health and disease dynamics in humans. The dual nature of this bacterium, being both part of the normal flora and a potential pathogen, illustrates the complex interactions within host-associated microbial ecosystems.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusActinomyces
SpeciesActinomyces naeslundii
Strainstrain UMB0181

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Actinomyces naeslundii strain UMB0181
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatsubmucosal sulcus
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Actinomyces naeslundii strain UMB0181 ERR1203670.17957_1_82.18,

Gene Summary

Adenine Count

502247 bp

Thymine Count

509308 bp

Guanine Count

1054574 bp

Cytosine Count

1053918 bp

Genome Length

3127787 bp

Protein-coding Genes

2536 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligaseCYJ18_04410Not AvailableNegative1026936 - 102840249398.9
udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2, 6-diaminopimelate ligaseCYJ18_04415Not AvailableNegative1028387 - 102997355800.0
peptidoglycan glycosyltransferaseCYJ18_04420Not AvailableNegative1030081 - 103188063253.3
hypothetical proteinCYJ18_04425Not AvailableNegative1031887 - 103236016249.5
16s rrna (cytosine(1402)-n(4))-methyltransferaseCYJ18_04430Not AvailableNegative1032473 - 103359439853.1
transcriptional regulator mrazCYJ18_04435Not AvailableNegative1033922 - 103435315885.1
duf3040 domain-containing proteinCYJ18_04440Not AvailableNegative1034904 - 103531714876.8
dna polymerase ivCYJ18_04445Not AvailableNegative1035488 - 103676845978.1
spermidine synthaseCYJ18_04450Not AvailablePositive1036985 - 103776127749.3
pac2 family proteinCYJ18_04455Not AvailableNegative1037795 - 103873333337.4

Displaying genes 851 – 860 of 2592 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Dental cariesCausesPMC6060398
ActinomycosisCausesPMC8962608
Infective endocarditisCausesPMC7059227

Displaying health effects 1 – 3 of 3 in total