Actinomyces naeslundii strain UMB0181

Gram-positiveFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Actinomyces

Description

Actinomyces naeslundii strain UMB0181 is a Gram-positive bacterium characterized as a facultative anaerobe. This strain is primarily found in the submucosal sulcus of the human host, Homo sapiens. It has a single replicon, which is indicative of its genomic structure. This bacterium is associated with several health effects, notably dental caries and actinomycosis. Dental caries, commonly known as tooth decay, highlights the role of A. naeslundii in oral microbiology and its potential contribution to the pathogenicity of dental diseases. Actinomycosis, a chronic bacterial infection, further emphasizes its clinical significance. The accessions for this strain are cataloged under PKKP00000000.1, providing a reference for researchers interested in studying its genetic and phenotypic characteristics. In terms of ecological insight, A. naeslundii's ability to thrive in the submucosal sulcus suggests its adaptation to a niche that supports both its survival and potential pathogenicity. This ecological role underscores the importance of understanding microbial communities in the oral cavity, as organisms like A. naeslundii contribute to health and disease dynamics in humans. The dual nature of this bacterium, being both part of the normal flora and a potential pathogen, illustrates the complex interactions within host-associated microbial ecosystems.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusActinomyces
SpeciesActinomyces naeslundii
Strainstrain UMB0181

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Actinomyces naeslundii strain UMB0181
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatsubmucosal sulcus
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Actinomyces naeslundii strain UMB0181 ERR1203670.17957_1_82.18,

Gene Summary

Adenine Count

502247 bp

Thymine Count

509308 bp

Guanine Count

1054574 bp

Cytosine Count

1053918 bp

Genome Length

3127787 bp

Protein-coding Genes

2536 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinCYJ18_00315Not AvailableNegative76503 - 7713221276.4
uracil-dna glycosylaseCYJ18_00320Not AvailablePositive77251 - 7792824193.3
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseCYJ18_00325Not AvailablePositive78105 - 7862317530.6
cysteine--trna ligaseCYJ18_00330Not AvailablePositive78769 - 8035857436.3
23s rrna (guanosine(2251)-2'-o)-methyltransferase rlmbCYJ18_00335Not AvailablePositive80424 - 8141935039.9
hypothetical proteinCYJ18_00340Not AvailablePositive81528 - 8276943258.6
hypothetical proteinCYJ18_00345Not AvailableNegative82931 - 8335015459.9
hypothetical proteinCYJ18_00355Not AvailableNegative84440 - 8490717322.2
duf4032 domain-containing proteinCYJ18_00360Not AvailableNegative85019 - 8639251821.4
sn-glycerol-3-phosphate abc transporter atp-binding protein ugpcCYJ18_00365Not AvailableNegative86646 - 8777340572.7

Displaying genes 61 – 70 of 2592 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Dental cariesCausesPMC6060398
ActinomycosisCausesPMC8962608
Infective endocarditisCausesPMC7059227

Displaying health effects 1 – 3 of 3 in total