Gardnerella vaginalis strain UMB0061

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis strain UMB0061 is a Gram-positive, rod-shaped bacterium that is classified as a chemoheterotroph, meaning it derives its energy from organic compounds. This strain is anaerobic, indicating that it thrives in environments devoid of oxygen. It is characterized by the absence of mobility, as it does not possess flagella, yet it has a single membrane and one replicon. The optimal growth temperature for Gardnerella vaginalis strain UMB0061 is 37°C, placing it within the mesophilic temperature range, which is typical for organisms associated with warm-blooded hosts. This strain is primarily free-living and has been identified in various hosts, including Homo sapiens, Metazoa, and Oryctolagus cuniculus. Clinically, Gardnerella vaginalis strain UMB0061 is associated with several health issues, particularly in humans, such as urinary tract infections (UTIs), pyogenic osteomyelitis, and bacterial vaginosis (BV). Its pathogenicity is notable, as it plays a significant role in the dysbiosis of the vaginal microbiome, leading to BV. Understanding the ecological role and health implications of Gardnerella vaginalis strain UMB0061 is crucial, particularly in the context of its interactions with host microbiomes and its contribution to various infections. This knowledge can inform clinical approaches to managing infections linked to this organism and enhance our understanding of microbial dynamics in the human body.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
Strainstrain UMB0061

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis strain UMB0061
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Gardnerella vaginalis strain UMB0061


Gene Summary

Adenine Count

513665 bp

Thymine Count

510691 bp

Guanine Count

358716 bp

Cytosine Count

358828 bp

Genome Length

1742219 bp

Protein-coding Genes

1337 genes

Non-Coding Genes

111 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna recombinaseCYJ58_07190Not AvailableNegative1692427 - 169283716341.7
Site-specific recombinaseCYJ58_07195Not AvailableNegative1692807 - 169440260989.2
hypothetical proteinCYJ58_07200Not AvailableNegative1694463 - 16946758213.9
rna polymerase subunit sigma-70CYJ58_07205Not AvailableNegative1694662 - 169507215869.1
EndolysinCYJ58_07210Not AvailableNegative1695223 - 169614334021.6
Phage holinCYJ58_07215Not AvailableNegative1696136 - 169655515331.0
toxinCYJ58_07220Not AvailableNegative1696716 - 169706913220.7
hypothetical proteinCYJ58_07225Not AvailableNegative1697050 - 16972326706.22
Putative phage tail proteinCYJ58_07230Not AvailableNegative1697278 - 1700085106106.0
Tail proteinCYJ58_07235Not AvailableNegative1700098 - 170076025411.4

Displaying genes 61 – 70 of 1448 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic osteomyelitisCausesPMC7852921
Bacterial vaginosisCausesPMC11597594
Bacterial vaginosisCausesPMC11782042
UtisCausesPMC11782042
Bacterial vaginosisCausesPMC12054147
BvCausesPMC12519793
BvCausesPMC12800088
Bacterial vaginosisCausesPMC13228082
BvCausesPMC13228082
Bacterial vaginosisCausesPMC12281154

Displaying health effects 1 – 10 of 11 in total