Gardnerella vaginalis strain UMB0061

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis strain UMB0061 is a Gram-positive, rod-shaped bacterium that is classified as a chemoheterotroph, meaning it derives its energy from organic compounds. This strain is anaerobic, indicating that it thrives in environments devoid of oxygen. It is characterized by the absence of mobility, as it does not possess flagella, yet it has a single membrane and one replicon. The optimal growth temperature for Gardnerella vaginalis strain UMB0061 is 37°C, placing it within the mesophilic temperature range, which is typical for organisms associated with warm-blooded hosts. This strain is primarily free-living and has been identified in various hosts, including Homo sapiens, Metazoa, and Oryctolagus cuniculus. Clinically, Gardnerella vaginalis strain UMB0061 is associated with several health issues, particularly in humans, such as urinary tract infections (UTIs), pyogenic osteomyelitis, and bacterial vaginosis (BV). Its pathogenicity is notable, as it plays a significant role in the dysbiosis of the vaginal microbiome, leading to BV. Understanding the ecological role and health implications of Gardnerella vaginalis strain UMB0061 is crucial, particularly in the context of its interactions with host microbiomes and its contribution to various infections. This knowledge can inform clinical approaches to managing infections linked to this organism and enhance our understanding of microbial dynamics in the human body.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
Strainstrain UMB0061

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis strain UMB0061
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Gardnerella vaginalis strain UMB0061 .16933_8_2.17, whole genome

Gene Summary

Adenine Count

513665 bp

Thymine Count

510691 bp

Guanine Count

358716 bp

Cytosine Count

358828 bp

Genome Length

1742219 bp

Protein-coding Genes

1337 genes

Non-Coding Genes

111 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
atp-dependent endonucleaseCYJ58_05870Not AvailableNegative1396400 - 139785752688.3
oligoribonucleaseCYJ58_05875Not AvailableNegative1397897 - 139860426658.6
hypothetical proteinCYJ58_05880Not AvailableNegative1398676 - 139905314720.8
hypothetical proteinCYJ58_05885Not AvailableNegative1399064 - 13993039086.0
imp dehydrogenaseCYJ58_05890Not AvailableNegative1399487 - 140103155004.0
undecaprenyl/decaprenyl-phosphate alpha-n-acetylglucosaminyl 1-phosphate transferaseCYJ58_05895Not AvailableNegative1401113 - 140221639507.4
threonylcarbamoyl-amp synthaseCYJ58_05900Not AvailableNegative1402213 - 140289924366.1
peptide chain release factor n(5)-glutamine methyltransferaseCYJ58_05905Not AvailableNegative1402892 - 140380033415.1
peptide chain release factor 1CYJ58_05910Not AvailableNegative1403867 - 140496440642.8
50s ribosomal protein l31CYJ58_05915Not AvailableNegative1405132 - 14053447837.38

Displaying genes 1231 – 1240 of 1448 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic osteomyelitisCausesPMC7852921
Bacterial vaginosisCausesPMC11597594
Bacterial vaginosisCausesPMC11782042
UtisCausesPMC11782042
Bacterial vaginosisCausesPMC12054147
BvCausesPMC12519793
BvCausesPMC12800088
Bacterial vaginosisCausesPMC13228082
BvCausesPMC13228082
Bacterial vaginosisCausesPMC12281154

Displaying health effects 1 – 10 of 11 in total