Enterococcus faecalis strain EN258

Enterococcus faecalis strain EN258 is a Gram-positive, non-motile cocci classified as a facultative anaerobe, which thrives optimally at 37°C within a mesophilic temperature range. This strain is a chemoorganotroph, deriving energy from organic compounds, and possesses a single membrane with one replicon. It exhibits a free-living biotic relationship, indicating its ability to exist independently in various environments. E. faecalis strain EN258 has a wide host range, including Homo sapiens, Gallus gallus, Bos, and several other Metazoa species such as Danio rerio and Sus scrofa, as well as various insects and domesticated animals like Canis lupus familiaris and Felis catus. This diverse host range underscores the strain's ecological adaptability and potential for cross-species transmission. In terms of health implications, E. faecalis strain EN258 is associated with numerous serious infections in humans, including bacteremia, urinary tract infections (UTIs), endocarditis, and meningitis, among others. It is particularly noted for its role in nosocomial infections, which highlights its significance in healthcare settings. The presence of this strain in various anatomical sites and its involvement in multiple infection types emphasizes its pathogenic potential. The ecological insight gleaned from E. faecalis strain EN258 is its ability to thrive in diverse environments and host organisms, which may enhance its survival and transmission in both natural and clinical contexts. This adaptability, combined with its pathogenic capabilities, makes E. faecalis an important subject of study in microbiology and infectious disease research.