Enterococcus faecium strain EN886

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain EN886 is a Gram-positive, cocci-shaped bacterium classified as a facultative anaerobe. It is primarily found in fermented mare milk, indicating its adaptability to specific ecological niches involving dairy fermentation. The strain possesses flagella, which may contribute to its motility in various environments. E. faecium EN886 has been associated with a range of hosts, including Homo sapiens, various species of birds (Aves), and mammals such as Bos taurus (cattle) and Sus scrofa (swine). This broad host range suggests that E. faecium has evolved mechanisms to survive in diverse biological systems, including both animals and humans. Notably, this strain is implicated in multiple health concerns, particularly in humans, where it is associated with serious conditions such as endocarditis, bloodstream infections, urinary tract infections, and nosocomial infections. The strain’s pathogenicity highlights its potential as a significant opportunistic pathogen, especially in hospital settings where patients may be vulnerable. The presence of E. faecium EN886 in fermented mare milk and its pathogenic capabilities underline its dual role in ecology and human health. While it contributes to traditional dairy processes, its potential to cause systemic infections in humans necessitates careful monitoring in clinical contexts. Understanding the ecology of E. faecium strains like EN886 could inform both food safety practices and public health strategies to mitigate the risks associated with its pathogenicity.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain EN886

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain EN886
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain EN886 NODE_182_length_208_cov_42.916,

Gene Summary

Adenine Count

863882 bp

Thymine Count

872218 bp

Guanine Count

520176 bp

Cytosine Count

526691 bp

Genome Length

2782967 bp

Protein-coding Genes

2644 genes

Non-Coding Genes

128 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nif3-like dinuclear metal center hexameric proteinCYQ86_06870Not AvailableNegative1387646 - 138876742146.4
trna (adenine(22)-n(1))-methyltransferase trmkCYQ86_06875Not AvailableNegative1388764 - 138946526512.0
hypothetical proteinCYQ86_06880Not AvailableNegative1389609 - 139004915445.5
primosomal protein dnaiCYQ86_06885Not AvailableNegative1390178 - 139110435448.4
replication initiation and membrane attachmentCYQ86_06890Not AvailableNegative1391104 - 139247752399.4
transcriptional repressor nrdrCYQ86_06895Not AvailableNegative1392500 - 139300319768.4
csbd family proteinCYQ86_06900Not AvailableNegative1393316 - 139364812831.8
dephospho-coa kinaseCYQ86_06905Not AvailableNegative1393698 - 139432723444.5
dna-formamidopyrimidine glycosylaseCYQ86_06910Not AvailableNegative1394291 - 139512731424.4
dna polymerase iCYQ86_06915Not AvailableNegative1395172 - 1397817100414.0

Displaying genes 1421 – 1430 of 2772 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total