Akkermansia muciniphila strain GP23

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP23 is a Gram-negative, anaerobic coccus that exhibits a cell arrangement characterized by pairs or singles. This strain is non-motile and does not possess flagella, which suggests a lifestyle adapted to its specific habitat. It is free-living and is primarily associated with hosts such as Homo sapiens and Metazoa, indicating its potential ecological relevance in these environments. The optimal growth temperature for A. muciniphila strain GP23 is 37°C, placing it within the mesophilic temperature range. It features a unique cellular structure with two membranes and contains a single replicon, which is characteristic of its genomic organization. From a health perspective, A. muciniphila strain GP23 has been associated with food allergies and the thinning of the jejunum mucus layer. These traits highlight its potential impact on gut health and the immune response in its human host. In summary, the presence of A. muciniphila strain GP23 in the gut microbiome reflects its role in maintaining mucosal barriers, while its associations with specific health conditions underscore the complex interactions between gut microbiota and host health. Understanding these relationships further emphasizes the significance of this strain in ecological and health-related contexts.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP23

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP23
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP23


Gene Summary

Adenine Count

638671 bp

Thymine Count

631943 bp

Guanine Count

789376 bp

Cytosine Count

799287 bp

Genome Length

2859287 bp

Protein-coding Genes

2442 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinCXT92_00005Not AvailableNegative357 - 254982544.5
hypothetical proteinCXT92_00010Not AvailableNegative2543 - 27467974.89
hypothetical proteinCXT92_00015Not AvailablePositive2824 - 320714549.7
hypothetical proteinCXT92_00020Not AvailablePositive3378 - 393521575.2
Trna-argNot AvailableNot AvailablePositive4373 - 4449Not Available
rrna maturation rnase ybeyCXT92_00030Not AvailableNegative4517 - 502618761.4
hdig domain-containing proteinCXT92_00035Not AvailableNegative4998 - 675864900.1
phosphate acyltransferase plsxCXT92_00040Not AvailableNegative6764 - 781337056.8
50s ribosomal protein l32CXT92_00045Not AvailableNegative7962 - 81536891.39
hypothetical proteinCXT92_00050Not AvailableNegative8177 - 865917714.6

Displaying genes 1 – 10 of 2498 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total