Akkermansia muciniphila strain GP36

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP36 is a Gram-negative, anaerobic bacterium characterized by its cocci shape and presence in pairs or singles. This strain is non-motile and does not possess flagella, indicating a lack of mobility. It thrives at an optimal temperature of 37°C, fitting within the mesophilic temperature range. Akkermansia muciniphila is a free-living organism found in host-associated environments, primarily associated with Homo sapiens and Metazoa. It has a unique biotic relationship with its hosts, influencing various health aspects. Notably, this strain is implicated in food allergy and is associated with the thinning of the jejunum mucus layer, which may have implications for gut health and immunity. With a single replicon and a double membrane structure, Akkermansia muciniphila strain GP36 is part of the diverse microbial communities that inhabit the gastrointestinal tract. Its presence and activities may play a crucial role in maintaining the integrity of the gut barrier and influencing immune responses. Understanding the characteristics and effects of Akkermansia muciniphila strain GP36 can provide insights into its potential role in human health, particularly regarding gut microbiota composition and functionality. The specific health effects associated with this strain highlight the importance of studying gut-associated microorganisms and their contributions to both health and disease.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP36

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP36
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP36 scaf-11, whole genome shotgun

Gene Summary

Adenine Count

625589 bp

Thymine Count

599770 bp

Guanine Count

736897 bp

Cytosine Count

787960 bp

Genome Length

2750232 bp

Protein-coding Genes

2321 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligaseCXU05_00760Not AvailablePositive165414 - 16691653454.2
phospho-n-acetylmuramoyl-pentapeptide- transferaseCXU05_00765Not AvailablePositive166922 - 16802539241.0
udp-n-acetylmuramoyl-l-alanine--d-glutamate ligaseCXU05_00770Not AvailablePositive168038 - 16939349079.2
hypothetical proteinCXU05_00775Not AvailablePositive169371 - 17017129364.7
hypothetical proteinCXU05_00780Not AvailablePositive170196 - 17133841811.0
undecaprenyldiphospho-muramoylpentapeptide beta-n-acetylglucosaminyltransferaseCXU05_00785Not AvailablePositive171335 - 17245940407.8
udp-n-acetylenolpyruvoylglucosamine reductaseCXU05_00790Not AvailablePositive172452 - 17474983102.7
d-alanine--d-alanine ligaseCXU05_00795Not AvailablePositive174772 - 17570733288.0
hypothetical proteinCXU05_00800Not AvailablePositive175755 - 17670536108.8
recombinase recaCXU05_00805Not AvailablePositive176931 - 17797137290.8

Displaying genes 151 – 160 of 2376 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total