Akkermansia muciniphila strain GP39

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP39 is a Gram-negative, non-motile, anaerobic bacterium characterized by its cocci shape and unique habitat associated with host organisms, specifically Homo sapiens and Metazoa. This strain is notable for its presence in pairs or singles, indicating its specific cell arrangement. It possesses two membranes and has a single replicon, suggesting a streamlined genetic structure. This strain thrives optimally at 37°C, falling within the mesophilic temperature range. As a free-living bacterium, Akkermansia muciniphila GP39 plays a significant role in the gut microbiome, influencing host health and potentially contributing to conditions like food allergies. Additionally, it has been associated with the thinning of the jejunum mucus layer, which may impact gut barrier function and overall gastrointestinal health. The health effects linked to this strain highlight its ecological significance in the gut environment, emphasizing the delicate balance within the microbiome and its relationship with host physiology. The interplay between Akkermansia muciniphila GP39 and its host could provide insights into microbial contributions to health and disease, particularly in the context of gut mucosal integrity and immune responses. Understanding the behavior and interactions of this strain within its ecological niche is essential for grasping its potential implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP39

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP39
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP39 scaf-23, whole genome shotgun

Gene Summary

Adenine Count

638849 bp

Thymine Count

647351 bp

Guanine Count

810703 bp

Cytosine Count

786432 bp

Genome Length

2883372 bp

Protein-coding Genes

2420 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
threonine--trna ligaseCXU07_04420Not AvailablePositive1037936 - 103982871585.0
translation initiation factor if-3CXU07_04425Not AvailablePositive1039868 - 104050624184.7
hypothetical proteinCXU07_04435Not AvailableNegative1041024 - 104230148007.4
1-deoxy-d-xylulose-5-phosphate reductoisomeraseCXU07_04440Not AvailableNegative1042261 - 104343642378.1
hypothetical proteinCXU07_04445Not AvailablePositive1043470 - 10437279035.61
pantetheine-phosphate adenylyltransferaseCXU07_04450Not AvailablePositive1043724 - 104423319669.8
peptide chain release factor-like proteinCXU07_04455Not AvailableNegative1044258 - 104462013813.7
hypothetical proteinCXU07_04460Not AvailableNegative1044607 - 104516119987.5
utp--glucose-1-phosphate uridylyltransferaseCXU07_04465Not AvailableNegative1045148 - 104653350383.3
methyltransferase type 11CXU07_04470Not AvailableNegative1046632 - 104737528902.3

Displaying genes 881 – 890 of 2477 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total