Akkermansia muciniphila strain GP39

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP39 is a Gram-negative, non-motile, anaerobic bacterium characterized by its cocci shape and unique habitat associated with host organisms, specifically Homo sapiens and Metazoa. This strain is notable for its presence in pairs or singles, indicating its specific cell arrangement. It possesses two membranes and has a single replicon, suggesting a streamlined genetic structure. This strain thrives optimally at 37°C, falling within the mesophilic temperature range. As a free-living bacterium, Akkermansia muciniphila GP39 plays a significant role in the gut microbiome, influencing host health and potentially contributing to conditions like food allergies. Additionally, it has been associated with the thinning of the jejunum mucus layer, which may impact gut barrier function and overall gastrointestinal health. The health effects linked to this strain highlight its ecological significance in the gut environment, emphasizing the delicate balance within the microbiome and its relationship with host physiology. The interplay between Akkermansia muciniphila GP39 and its host could provide insights into microbial contributions to health and disease, particularly in the context of gut mucosal integrity and immune responses. Understanding the behavior and interactions of this strain within its ecological niche is essential for grasping its potential implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP39

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP39
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP39 scaf-23, whole genome shotgun

Gene Summary

Adenine Count

638849 bp

Thymine Count

647351 bp

Guanine Count

810703 bp

Cytosine Count

786432 bp

Genome Length

2883372 bp

Protein-coding Genes

2420 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dihydroorotaseCXU07_08670Not AvailablePositive1998372 - 199965245629.9
trna (n6-threonylcarbamoyladenosine(37)-n6)-methyltransferase trmoCXU07_08675Not AvailablePositive1999709 - 200039825585.6
hypothetical proteinCXU07_08680Not AvailableNegative2000476 - 200103922201.7
hypothetical proteinCXU07_08690Not AvailablePositive2002204 - 200248811568.1
hypothetical proteinCXU07_08695Not AvailableNegative2002834 - 200314211774.9
transcriptional regulatorCXU07_08700Not AvailableNegative2003223 - 20034026902.58
hypothetical proteinCXU07_08705Not AvailablePositive2003718 - 200402611316.0
hypothetical proteinCXU07_08710Not AvailableNegative2004179 - 20043918097.82
marr family transcriptional regulatorCXU07_08715Not AvailablePositive2004428 - 200486816724.4
hypothetical proteinCXU07_08720Not AvailablePositive2004911 - 200628749281.7

Displaying genes 1721 – 1730 of 2477 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total