Akkermansia muciniphila strain GP39

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP39 is a Gram-negative, non-motile, anaerobic bacterium characterized by its cocci shape and unique habitat associated with host organisms, specifically Homo sapiens and Metazoa. This strain is notable for its presence in pairs or singles, indicating its specific cell arrangement. It possesses two membranes and has a single replicon, suggesting a streamlined genetic structure. This strain thrives optimally at 37°C, falling within the mesophilic temperature range. As a free-living bacterium, Akkermansia muciniphila GP39 plays a significant role in the gut microbiome, influencing host health and potentially contributing to conditions like food allergies. Additionally, it has been associated with the thinning of the jejunum mucus layer, which may impact gut barrier function and overall gastrointestinal health. The health effects linked to this strain highlight its ecological significance in the gut environment, emphasizing the delicate balance within the microbiome and its relationship with host physiology. The interplay between Akkermansia muciniphila GP39 and its host could provide insights into microbial contributions to health and disease, particularly in the context of gut mucosal integrity and immune responses. Understanding the behavior and interactions of this strain within its ecological niche is essential for grasping its potential implications for human health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP39

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP39
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP39 scaf-23, whole genome shotgun

Gene Summary

Adenine Count

638849 bp

Thymine Count

647351 bp

Guanine Count

810703 bp

Cytosine Count

786432 bp

Genome Length

2883372 bp

Protein-coding Genes

2420 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinCXU07_08015Not AvailableNegative1853744 - 185499746059.7
fe-s cluster assembly protein sufbCXU07_08020Not AvailableNegative1855009 - 185644553464.2
fe-s cluster assembly atpase sufcCXU07_08025Not AvailableNegative1856469 - 185723028081.8
transcriptional repressorCXU07_08030Not AvailableNegative1857243 - 185768316549.8
50s ribosomal protein l27CXU07_08035Not AvailableNegative1857839 - 18581029526.45
50s ribosomal protein l21CXU07_08040Not AvailableNegative1858129 - 185844611573.2
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex atpase subunit type 1 tsaeCXU07_08045Not AvailablePositive1858535 - 185898416507.6
hypothetical proteinCXU07_08050Not AvailableNegative1858993 - 185981129928.7
hypothetical proteinCXU07_08055Not AvailableNegative1859808 - 186027516545.4
hypothetical proteinCXU07_08060Not AvailablePositive1860300 - 186268487767.0

Displaying genes 1591 – 1600 of 2477 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total