Akkermansia muciniphila strain GP43

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP43 is a Gram-negative, anaerobic bacterium characterized by its cocci shape and the absence of mobility, as it lacks flagella. This strain is part of the host-associated microbiome and is primarily found in Homo sapiens and Metazoa. It typically exists in pairs or singles, contributing to its free-living biotic relationship. A. muciniphila strain GP43 thrives at an optimal temperature of 37°C and falls within the mesophilic temperature range. Its cellular structure is notable for having two membranes and a single replicon, which is characteristic of many Gram-negative bacteria. In terms of health effects, this strain has been implicated in food allergies and is associated with the thinning of the jejunum mucus layer. These effects may have significant implications for gut health and the overall well-being of the host. Understanding the role of A. muciniphila strain GP43 could provide insights into its potential therapeutic applications, particularly in managing gut-related conditions. Overall, the presence and functions of Akkermansia muciniphila strain GP43 highlight its ecological significance in the gut microbiome, where it may influence host health through its interactions with intestinal mucus and immune responses. This underscores the importance of studying specific strains within the microbiome to elucidate their roles in health and disease.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP43

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP43
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP43 scaf-11, whole genome shotgun

Gene Summary

Adenine Count

633830 bp

Thymine Count

608253 bp

Guanine Count

752663 bp

Cytosine Count

800805 bp

Genome Length

2795610 bp

Protein-coding Genes

2346 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-alanyl-d-alanine carboxypeptidaseCXU09_04815Not AvailablePositive1105396 - 110631933548.7
redox-regulated atpase ychfCXU09_04820Not AvailablePositive1106378 - 110749940766.6
glycine cleavage system protein tCXU09_04825Not AvailablePositive1107575 - 110866039006.8
glycine cleavage system protein hCXU09_04830Not AvailablePositive1108731 - 110911113719.7
glycine dehydrogenase (aminomethyl-transferring)CXU09_04835Not AvailablePositive1109207 - 1112053102676.0
hypothetical proteinCXU09_04840Not AvailablePositive1112310 - 111337439597.7
duf805 domain-containing proteinCXU09_04845Not AvailableNegative1113406 - 111403823260.2
sulfataseCXU09_04850Not AvailableNegative1114047 - 111620678981.8
hypothetical proteinCXU09_04855Not AvailableNegative1116625 - 111848169074.1
hypothetical proteinCXU09_04860Not AvailablePositive1118631 - 111943429113.2

Displaying genes 961 – 970 of 2403 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total