Akkermansia muciniphila strain GP43

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP43 is a Gram-negative, anaerobic bacterium characterized by its cocci shape and the absence of mobility, as it lacks flagella. This strain is part of the host-associated microbiome and is primarily found in Homo sapiens and Metazoa. It typically exists in pairs or singles, contributing to its free-living biotic relationship. A. muciniphila strain GP43 thrives at an optimal temperature of 37°C and falls within the mesophilic temperature range. Its cellular structure is notable for having two membranes and a single replicon, which is characteristic of many Gram-negative bacteria. In terms of health effects, this strain has been implicated in food allergies and is associated with the thinning of the jejunum mucus layer. These effects may have significant implications for gut health and the overall well-being of the host. Understanding the role of A. muciniphila strain GP43 could provide insights into its potential therapeutic applications, particularly in managing gut-related conditions. Overall, the presence and functions of Akkermansia muciniphila strain GP43 highlight its ecological significance in the gut microbiome, where it may influence host health through its interactions with intestinal mucus and immune responses. This underscores the importance of studying specific strains within the microbiome to elucidate their roles in health and disease.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP43

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP43
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP43 scaf-11, whole genome shotgun

Gene Summary

Adenine Count

633830 bp

Thymine Count

608253 bp

Guanine Count

752663 bp

Cytosine Count

800805 bp

Genome Length

2795610 bp

Protein-coding Genes

2346 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fmdb family transcriptional regulatorCXU09_05415Not AvailableNegative1243463 - 12437239768.9
30s ribosomal protein s14CXU09_05420Not AvailableNegative1243796 - 124406510284.7
hypothetical proteinCXU09_05425Not AvailableNegative1244783 - 12450499347.42
argininosuccinate synthaseCXU09_05430Not AvailablePositive1245077 - 124636947875.2
arylsulfataseCXU09_05435Not AvailablePositive1246471 - 124803057611.4
hypothetical proteinCXU09_05440Not AvailablePositive1248117 - 124935546093.8
triose-phosphate isomeraseCXU09_05445Not AvailablePositive1249408 - 125017226869.3
prepilin-type cleavage/methylation domain-containing proteinCXU09_05450Not AvailablePositive1250320 - 125100324954.9
hypothetical proteinCXU09_05455Not AvailablePositive1251134 - 125174522749.1
arylsulfataseCXU09_05460Not AvailablePositive1251904 - 125349659417.3

Displaying genes 1081 – 1090 of 2403 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total