Akkermansia muciniphila strain GP30

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP30 is a Gram-negative anaerobic bacterium characterized by its cocci shape and non-motility. It exists predominantly in pairs or as singles and is part of the host-associated microbiota, specifically found in Homo sapiens and other Metazoa. This strain has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the physiological temperature of the human body. Notably, Akkermansia muciniphila strain GP30 is free-living, suggesting it plays a significant role in the gut microbiome. It possesses a unique structure with two membranes and a single replicon, indicating its distinct cellular organization. The bacterium has been associated with various health effects, including food allergies and the thinning of the jejunum mucus layer, which may have implications for gut health and overall well-being. Given its role in the gut microbiome and its association with specific health outcomes, Akkermansia muciniphila strain GP30 serves as an important microbial species in understanding the complex interactions within the human gut ecosystem. Its presence and activity could influence host health, particularly in the context of mucosal barrier integrity and immune responses. This underscores the necessity for further investigation into its functional roles and potential therapeutic applications in promoting gut health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP30

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP30
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP30 scaf-21, whole genome shotgun

Gene Summary

Adenine Count

664895 bp

Thymine Count

680095 bp

Guanine Count

944698 bp

Cytosine Count

899119 bp

Genome Length

3188864 bp

Protein-coding Genes

2605 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nadph-dependent fmn reductaseCXU19_00850Not AvailablePositive219040 - 21957619729.1
hypothetical proteinCXU19_00855Not AvailablePositive219979 - 22033212509.3
hypothetical proteinCXU19_00860Not AvailablePositive220561 - 22183847268.2
eama family transporterCXU19_00865Not AvailablePositive221860 - 22287036102.7
duf3737 domain-containing proteinCXU19_00870Not AvailablePositive223146 - 22401833154.1
cystathionine beta-lyaseCXU19_00875Not AvailablePositive224015 - 22519043965.6
ferredoxinCXU19_00880Not AvailablePositive225267 - 22627436434.4
2,5-diketo-d-gluconic acid reductaseCXU19_00885Not AvailablePositive226324 - 22717231934.0
alpha/beta hydrolaseCXU19_00890Not AvailablePositive227194 - 22827339339.3
metallophosphoesteraseCXU19_00895Not AvailablePositive228414 - 22955341172.1

Displaying genes 171 – 180 of 2661 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total