Akkermansia muciniphila strain GP30

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain GP30 is a Gram-negative anaerobic bacterium characterized by its cocci shape and non-motility. It exists predominantly in pairs or as singles and is part of the host-associated microbiota, specifically found in Homo sapiens and other Metazoa. This strain has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the physiological temperature of the human body. Notably, Akkermansia muciniphila strain GP30 is free-living, suggesting it plays a significant role in the gut microbiome. It possesses a unique structure with two membranes and a single replicon, indicating its distinct cellular organization. The bacterium has been associated with various health effects, including food allergies and the thinning of the jejunum mucus layer, which may have implications for gut health and overall well-being. Given its role in the gut microbiome and its association with specific health outcomes, Akkermansia muciniphila strain GP30 serves as an important microbial species in understanding the complex interactions within the human gut ecosystem. Its presence and activity could influence host health, particularly in the context of mucosal barrier integrity and immune responses. This underscores the necessity for further investigation into its functional roles and potential therapeutic applications in promoting gut health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
Strainstrain GP30

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila strain GP30
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain GP30 scaf-21, whole genome shotgun

Gene Summary

Adenine Count

664895 bp

Thymine Count

680095 bp

Guanine Count

944698 bp

Cytosine Count

899119 bp

Genome Length

3188864 bp

Protein-coding Genes

2605 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseCXU19_08230Not AvailableNegative2011302 - 201181117532.4
inositol monophosphataseCXU19_08235Not AvailableNegative2011838 - 201260228424.1
hypothetical proteinCXU19_08240Not AvailableNegative2012633 - 201442366695.8
hypothetical proteinCXU19_08245Not AvailableNegative2014448 - 201688090484.4
biopolymer transporter exbdCXU19_08250Not AvailableNegative2016877 - 201732316365.9
mota/tolq/exbb proton channel family proteinCXU19_08255Not AvailableNegative2017360 - 201815128309.8
excinuclease abc subunit uvrcCXU19_08260Not AvailablePositive2018336 - 201983256379.8
23s rrna (pseudouridine(1915)-n(3))-methyltransferase rlmhCXU19_08265Not AvailablePositive2019839 - 202027616406.2
hypothetical proteinCXU19_08270Not AvailableNegative2020281 - 202071515542.8
30s ribosomal protein s9CXU19_08275Not AvailableNegative2020833 - 202122814742.9

Displaying genes 1641 – 1650 of 2661 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total