Prevotella intermedia strain KCOM 1653

Prevotella intermedia strain KCOM 1653 is a Gram-negative, anaerobic bacterium characterized by its rod shape and presence of flagella. This strain is primarily found in various habitats associated with humans, including the gingival sulci, oral cavity, gut, rumen, subgingival and supragingival dental biofilms, subgingival plaque, and the urogenital tract. P. intermedia is known to have significant health implications, particularly in the context of oral health. It is associated with several periodontal diseases such as periodontal inflammation, periapical periodontitis, and periodontal abscesses. Additionally, it has been implicated in dental caries and more severe health issues like intracranial infections and noma. The bacterium's pathogenicity is specifically noted in humans, indicating its role in various infections and inflammatory conditions. The presence of P. intermedia in diverse anatomical niches highlights its ecological adaptability and potential impact on human health. The bacterium's ability to thrive in anaerobic environments, such as dental biofilms and the gut, suggests its role in maintaining the microbial balance within these ecosystems. Furthermore, its association with periodontal disease underscores the importance of oral microbiota in systemic health, revealing that disturbances in these communities can lead to significant health consequences. This illustrates the intricate relationship between microbial inhabitants and their hosts, emphasizing the need for continued research into oral and systemic health interactions.