Prevotella intermedia strain KCOM 1653

Prevotella intermedia strain KCOM 1653 is a Gram-negative, rod-shaped bacterium that thrives in anaerobic environments. This species is notably found in diverse habitats including the gingival sulci, gut, oral cavity, rumen, and both subgingival and supragingival dental biofilms, as well as in subgingival plaque and the urogenital tract. The presence of Prevotella intermedia in these specific ecological niches suggests its potential role in oral and gastrointestinal microbiomes, where it may contribute to the complex interspecies interactions characteristic of these communities. As an obligate anaerobe, Prevotella intermedia relies on environments devoid of oxygen to survive and grow, indicating its adaptation to localized niches within the human body where oxygen levels are minimal. The strain's association with dental biofilms highlights its potential involvement in oral health, particularly in relation to periodontal disease, although specific pathogenicity has not been detailed in the available data. Importantly, the diverse habitats of this strain point to its possible significance in both health and disease states, providing a unique perspective on its ecological role in maintaining homeostasis within the microbiota of humans and ruminants alike. Further investigations into its interactions within these environments may elucidate its contributions to microbial community dynamics.