Klebsiella pneumoniae strain PN030E4

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain PN030E4 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism as a chemoheterotroph. This strain is capable of existing in various forms, including singles, pairs, and chains, and possesses flagella, enabling mobility. Its optimal growth temperature is 37°C, which places it within the mesophilic temperature range. This strain is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants. Notably, it has been implicated in various health conditions, such as bacteremia, urinary tract infections, pneumonia, and liver abscesses, among others. Its pathogenicity is primarily directed towards humans, making it a significant concern in clinical microbiology. Klebsiella pneumoniae strain PN030E4 does not form spores and has a biotic relationship categorized as free-living. It contains a single replicon and features a double membrane structure, characteristic of its Gram-negative classification. From an ecological perspective, the presence of Klebsiella pneumoniae in diverse environments and its ability to infect multiple hosts highlight its adaptive nature and potential impact on both human health and animal populations. Its role in various infections underscores the importance of understanding its pathogenic mechanisms and the environmental factors that contribute to its survival and transmission.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain PN030E4

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain PN030E4
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain PN030E4 PN030E4_contig_2885, whole

Gene Summary

Adenine Count

1331949 bp

Thymine Count

1331808 bp

Guanine Count

1774526 bp

Cytosine Count

1780740 bp

Genome Length

6220887 bp

Protein-coding Genes

7046 genes

Non-Coding Genes

110 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l1CSC88_26205Not AvailableNegative5091715 - 509241924746.1
50s ribosomal protein l11CSC88_26210Not AvailableNegative5092423 - 509285114876.2
transcription termination/antitermination protein nusgCSC88_26215Not AvailableNegative5093008 - 509355320546.7
preprotein translocase subunit seceCSC88_26220Not AvailableNegative5093555 - 509393813616.3
hypothetical proteinCSC88_26225Not AvailableNegative5094031 - 50942618207.92
dna-binding response regulatorCSC88_26230Not AvailableNegative5094375 - 509487118620.2
hypothetical proteinCSC88_26235Not AvailablePositive5094872 - 50950827415.1
alkylhydroperoxidaseCSC88_26240Not AvailablePositive5095083 - 50952917250.64
hypothetical proteinCSC88_26245Not AvailableNegative5095312 - 50954284391.09
trna 2-thiocytidine(32) synthetase ttcaCSC88_26250Not AvailableNegative5095730 - 50959678918.78

Displaying genes 5041 – 5050 of 7156 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total