Bacteroides fragilis strain 12905

Bacteroides fragilis strain 12905 is a Gram-negative, rod-shaped bacterium that is classified as a chemoorganotroph, indicating that it derives energy from organic compounds. This organism is strictly anaerobic, thriving in environments devoid of oxygen, and is commonly found in host-associated habitats. It has a single replicon and features a double membrane structure. The strain exhibits a free-living biotic relationship and can inhabit various hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. Its optimal growth temperature is 37°C, placing it in the mesophilic temperature range, which is conducive to its survival in warm-blooded hosts. Bacteroides fragilis strain 12905 is recognized for its pathogenicity in humans, being implicated in several serious health conditions. These include bacteremia, abscesses, various gastrointestinal disorders such as diarrhea and colitis, as well as more severe outcomes like septicemia, colorectal cancer, and local tissue infections. The strain's ability to cause intraabdominal abscesses and its involvement in anaerobic infections highlight its clinical significance. The ecological insight into Bacteroides fragilis strain 12905 reveals its dual role in the microbiota of its hosts. While it can contribute to pathologies under certain conditions, it also plays a part in the normal gut flora, suggesting a complex interplay between the bacterium and host health. Its free-living nature and association with multiple host species underscore its adaptability and potential impact on both individual health and broader ecological systems.