Megamonas hypermegale strain NCTC10570

anaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Negativicutes

Order

Selenomonadales

Family

Selenomonadaceae

Genus

Megamonas

Description

Megamonas hypermegale strain NCTC10570 is a Gram-negative bacterium characterized by its anaerobic metabolism and presence of flagella, which facilitate motility in its habitat. This organism is primarily found in the cecal contents, suggesting a role in the gastrointestinal environment of host organisms. The strain NCTC10570 possesses a single replicon, indicative of its genomic structure, which may influence its replication and stability. The accession number for this strain is NZ_LT906446.1, which provides a reference for researchers seeking genomic and taxonomic information. The anaerobic nature of Megamonas hypermegale suggests that it thrives in low-oxygen environments, typical of the cecal region. This habitat is crucial for various microbial communities that contribute to digestion and fermentation processes within the host. The presence of flagella may enhance its ability to navigate through the viscous content of the cecum, potentially allowing it to exploit nutrient sources more effectively. Understanding the characteristics of Megamonas hypermegale, particularly its habitat and metabolic requirements, highlights its potential role in the complex ecosystem of the gut microbiome. This bacterium may contribute to the breakdown of complex carbohydrates or other substrates, playing a significant part in nutrient cycling and overall gut health. Further research on this strain could illuminate its functional contributions to the microbiota and its interactions with other microbial species within the cecal environment.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassNegativicutes
OrderSelenomonadales
FamilySelenomonadaceae
GenusMegamonas
SpeciesMegamonas hypermegale
Strainstrain NCTC10570

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatcecal contents
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Megamonas hypermegale strain NCTC10570 chromosome 1, complete

Gene Summary

Adenine Count

738214 bp

Thymine Count

738900 bp

Guanine Count

373578 bp

Cytosine Count

379650 bp

Genome Length

2230342 bp

Protein-coding Genes

2086 genes

Non-Coding Genes

74 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
vitamin b12 dependent-methionine synthase activation domain-containing proteinCKV65_RS09600Not AvailablePositive1991356 - 199205126137.6
homocysteine s-methyltransferase family proteinCKV65_RS09605Not AvailablePositive1992083 - 199445884476.3
protein-tyrosine-phosphataseCKV65_RS09610Not AvailableNegative1994523 - 199548837774.8
lysr family transcriptional regulatorCKV65_RS09615Not AvailableNegative1995541 - 199642233485.1
azlc family abc transporter permeaseCKV65_RS09620Not AvailablePositive1996532 - 199726926722.0
azld domain-containing proteinCKV65_RS09625Not AvailablePositive1997259 - 199757011379.5
atp-dependent 6-phosphofructokinaseCKV65_RS09630Not AvailableNegative1997654 - 199861934583.3
phosphoribosylaminoimidazolecarboxamide formyltransferaseCKV65_RS09635Not AvailablePositive1998888 - 200006343551.9
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinaseCKV65_RS09640Not AvailableNegative2000115 - 200089427602.5
phospholipid carrier-dependent glycosyltransferaseCKV65_RS09645Not AvailablePositive2001051 - 200273965323.1

Displaying genes 1931 – 1940 of 2160 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

288 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 288 metabolites

Health Effects

Health ConditionRelationReference
NafldCausesPMC9767906

Displaying health effects 1 – 1 of 1 in total