Akkermansia glycaniphila

ovoidanaerobic

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia glycaniphila is a Gram-negative, anaerobic bacterium characterized by its ovoid shape and non-motile nature. This species is part of the mesophilic temperature range, with an optimal growth temperature of 29°C. A notable feature of A. glycaniphila is its single replicon, which is an important aspect of its genetic organization. The ability of A. glycaniphila to thrive in anaerobic conditions suggests its ecological role may be significant in environments where oxygen is limited, such as the human gastrointestinal tract. This bacterium is likely to contribute to the gut microbiome, where it may play a role in the fermentation of dietary fibers, potentially influencing host metabolism and immune function. The presence of a true flagellum, despite its non-motility, may indicate adaptations for environmental interactions rather than locomotion. This could be relevant for its attachment to mucosal surfaces or for interacting with other microbial community members in the gut. In summary, A. glycaniphila exemplifies an anaerobic, Gram-negative bacterium with distinct morphological and physiological traits that underscore its potential ecological importance, particularly in the context of gut health and microbiome dynamics. Further research could elucidate its specific roles and contributions to gut ecology.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia glycaniphila
StrainNo strain

Profile

Physiology
Gram staining propertiesGram-negative
Shapeovoid
Mobilitynon-motile
Flagellar presenceYes
Number of membranesNot Available
Image of Akkermansia glycaniphila
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperature29
Temperature rangemesophilic
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia glycaniphila isolate APytT chromosome I, complete

Gene Summary

Adenine Count

664540 bp

Thymine Count

637461 bp

Guanine Count

866647 bp

Cytosine Count

905430 bp

Genome Length

3074078 bp

Protein-coding Genes

2514 genes

Non-Coding Genes

62 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
substrate-binding domain-containing proteinPYTT_RS05955Not AvailablePositive1414400 - 141548240580.9
trypsin-like peptidase domain-containing proteinPYTT_RS13315Not AvailableNegative1415522 - 141698552615.6
dna polymerase iii subunit deltaPYTT_RS05965Not AvailablePositive1417103 - 141819440264.1
trna uridine-5-carboxymethylaminomethyl(34) synthesis enzyme mnmgPYTT_RS05970Not AvailablePositive1418196 - 142006769459.3
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ribdPYTT_RS05975Not AvailableNegative1420261 - 142132239101.9
daph/dapd/glmu-related proteinPYTT_RS05980Not AvailablePositive1421710 - 142261832705.8
pep-cterm sorting domain-containing proteinPYTT_RS12985Not AvailablePositive1423270 - 142398925366.8
pep-cterm sorting domain-containing proteinPYTT_RS12990Not AvailablePositive1424393 - 142511225387.8
autotransporter domain-containing proteinPYTT_RS06005Not AvailableNegative1425344 - 1430260164860.0
hypothetical proteinPYTT_RS06010Not AvailableNegative1430425 - 143208060486.0

Displaying genes 1201 – 1210 of 2576 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.