Enterococcus faecalis strain NCTC8732

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain NCTC8732 is a Gram-positive, cocci-shaped bacterium classified as a chemoorganotroph and a facultative anaerobe. It thrives optimally at 37°C and is categorized as mesophilic. This strain possesses one membrane and one replicon, indicating a simple cellular structure. Notably, it is non-motile, lacking flagella. E. faecalis NCTC8732 is free-living and can inhabit various environments, including those associated with multiple host species. Its known hosts range from Homo sapiens and domesticated animals such as Gallus gallus (chickens) and Sus scrofa (pigs) to aquatic species like Lutjanus russellii (fish) and Danio rerio (zebrafish), as well as various invertebrates and mammals, including Canis lupus familiaris (dogs) and Felis catus (cats). This strain is clinically significant due to its pathogenicity in humans. It is associated with a wide array of health complications, including bacteremia, urinary tract infections (UTIs), endocarditis, meningitis, and infections at surgical sites. The bacterium is implicated in both nosocomial infections and various infectious lesions, particularly in the urinary tract, intra-abdomen, and oral cavity. The ecological insight drawn from E. faecalis NCTC8732's diverse host range and its ability to cause a multitude of infections underscores its adaptability and potential as an opportunistic pathogen in both clinical settings and natural environments. Its versatility highlights the importance of monitoring this organism in both health and disease contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain NCTC8732

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain NCTC8732
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain NCTC8732 chromosome 1.

Gene Summary

Adenine Count

894310 bp

Thymine Count

894701 bp

Guanine Count

541938 bp

Cytosine Count

533471 bp

Genome Length

2864420 bp

Protein-coding Genes

2578 genes

Non-Coding Genes

266 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiamine diphosphokinaseFGL29_RS13750Not AvailableNegative2640533 - 264117724146.6
ribulose-phosphate 3-epimeraseFGL29_RS13755Not AvailableNegative2641174 - 264182723677.5
ribosome small subunit-dependent gtpase aFGL29_RS13760Not AvailableNegative2641851 - 264274433847.7
serine/threonine protein kinase irekFGL29_RS13765Not AvailableNegative2642993 - 264514977376.1
stp1/irep family pp2c-type ser/thr phosphataseFGL29_RS13770Not AvailableNegative2645146 - 264589527503.3
16s rrna (cytosine(967)-c(5))-methyltransferase rsmbFGL29_RS13775Not AvailableNegative2645897 - 264727651475.3
methionyl-trna formyltransferaseFGL29_RS13780Not AvailableNegative2647282 - 264822334285.9
peptide deformylaseFGL29_RS13785Not AvailableNegative2648216 - 264871018739.3
primosomal protein n'FGL29_RS13790Not AvailableNegative2648737 - 265116992559.6
dna-directed rna polymerase subunit omegaFGL29_RS13795Not AvailableNegative2651324 - 265162611672.8

Displaying genes 2641 – 2650 of 2844 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total