Enterococcus faecalis strain NCTC8732

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain NCTC8732 is a Gram-positive, cocci-shaped bacterium classified as a chemoorganotroph and a facultative anaerobe. It thrives optimally at 37°C and is categorized as mesophilic. This strain possesses one membrane and one replicon, indicating a simple cellular structure. Notably, it is non-motile, lacking flagella. E. faecalis NCTC8732 is free-living and can inhabit various environments, including those associated with multiple host species. Its known hosts range from Homo sapiens and domesticated animals such as Gallus gallus (chickens) and Sus scrofa (pigs) to aquatic species like Lutjanus russellii (fish) and Danio rerio (zebrafish), as well as various invertebrates and mammals, including Canis lupus familiaris (dogs) and Felis catus (cats). This strain is clinically significant due to its pathogenicity in humans. It is associated with a wide array of health complications, including bacteremia, urinary tract infections (UTIs), endocarditis, meningitis, and infections at surgical sites. The bacterium is implicated in both nosocomial infections and various infectious lesions, particularly in the urinary tract, intra-abdomen, and oral cavity. The ecological insight drawn from E. faecalis NCTC8732's diverse host range and its ability to cause a multitude of infections underscores its adaptability and potential as an opportunistic pathogen in both clinical settings and natural environments. Its versatility highlights the importance of monitoring this organism in both health and disease contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain NCTC8732

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain NCTC8732
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain NCTC8732 chromosome 1.

Gene Summary

Adenine Count

894310 bp

Thymine Count

894701 bp

Guanine Count

541938 bp

Cytosine Count

533471 bp

Genome Length

2864420 bp

Protein-coding Genes

2578 genes

Non-Coding Genes

266 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-directed rna polymerase subunit betaFGL29_RS11745Not AvailableNegative2250050 - 22502266622.53
udp-n-acetylglucosamine 1-carboxyvinyltransferaseFGL29_RS11750Not AvailableNegative2250240 - 225154146989.1
duf1146 family proteinFGL29_RS11755Not AvailableNegative2251644 - 22518809209.63
f0f1 atp synthase subunit epsilonFGL29_RS11760Not AvailableNegative2252069 - 225248815478.5
f0f1 atp synthase subunit betaFGL29_RS11765Not AvailableNegative2252505 - 225391150809.6
f0f1 atp synthase subunit gammaFGL29_RS11770Not AvailableNegative2253985 - 225489333233.4
f0f1 atp synthase subunit alphaFGL29_RS11775Not AvailableNegative2254909 - 225646556186.3
atp synthase f1 subunit deltaFGL29_RS11780Not AvailableNegative2256494 - 225703620889.3
f0f1 atp synthase subunit bFGL29_RS11785Not AvailableNegative2257023 - 225755319454.4
atp synthase f0 subunit cFGL29_RS11790Not AvailableNegative2257691 - 22579127619.65

Displaying genes 2261 – 2270 of 2844 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total