Corynebacterium pseudotuberculosis strain NCTC4656

Corynebacterium pseudotuberculosis strain NCTC4656 is a Gram-positive bacterium notable for its pathogenicity primarily in animal hosts, including Homo sapiens, Ovis aries (sheep), Capra hircus (goats), and members of the Cervidae family (deer). This strain possesses a single replicon, which is characteristic of many bacterial species. This organism is associated with several health conditions, particularly in livestock. It is known to cause caseous lymphadenitis (CL), a chronic disease characterized by the formation of abscesses in lymph nodes, which can significantly impact animal health and agricultural productivity. Additionally, C. pseudotuberculosis has been implicated in other infections such as ulcerative lymphangitis, arthritis, bursitis, and superficial abscesses, indicating its role as a pathogen capable of causing a diverse range of suppurative infections. The pathogenic nature of C. pseudotuberculosis emphasizes its significance in veterinary medicine and public health, especially considering its ability to infect humans as well. The strain is cataloged under the accession number NZ_LR590478.1, which provides a reference for further genomic and phenotypic studies. Ecologically, C. pseudotuberculosis's presence in both domestic and wild animal populations suggests it may play a role in the complex interactions within these ecosystems, particularly concerning disease dynamics and the health of livestock. Understanding its pathogenic mechanisms can aid in developing strategies for disease prevention and management in affected animal populations.