Metamycoplasma orale strain NCTC10112

Gram-negativePleomorphicNon-motile

Kingdom

Bacillati

Phylum

Mycoplasmatota

Class

Order

Mycoplasmoidales

Family

Metamycoplasmataceae

Genus

Metamycoplasma

Description

Metamycoplasma orale strain NCTC10112 is a pleomorphic, gram-negative bacterium classified as a chemoheterotroph, indicating that it derives energy from organic compounds. This strain is notable for its lack of mobility, as it does not possess flagella despite their presence in the broader Mycoplasma genus. It thrives optimally at 37°C and falls within the mesophilic temperature range. This bacterium has been identified in multiple habitats and is specifically associated with Homo sapiens as its host. Clinically, Metamycoplasma orale strain NCTC10112 is linked to significant health issues, including osteomyelitis and osteonecrosis, which can have serious implications for bone health and recovery. The organism has two replicons, as indicated by its genomic data, with specific accessions NZ_LR214940.1 and NZ_LR214943.1 available for further research. Importantly, Metamycoplasma orale strain NCTC10112 does not undergo sporulation, which may influence its survival and pathogenicity in various environments. Understanding the pathogenic potential of Metamycoplasma orale strain NCTC10112 in the context of human health underscores the importance of continued research on its ecological niche and interactions within human hosts. This bacterium exemplifies the complex relationship between microbial inhabitants and host health, highlighting the need for awareness regarding its potential impact on bone-related diseases.

Taxonomy

KingdomBacillati
PhylumMycoplasmatota
Class/taxonomy?kingdom=Bacillati&level=klass&phylum=Mycoplasmatota
OrderMycoplasmoidales
FamilyMetamycoplasmataceae
GenusMetamycoplasma
SpeciesMetamycoplasma orale
Strainstrain NCTC10112

Profile

Physiology
Gram staining propertiesNegative
ShapePleomorphic
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Metamycoplasma orale strain NCTC10112


Gene Summary

Adenine Count

275890 bp

Thymine Count

274265 bp

Guanine Count

94355 bp

Cytosine Count

92354 bp

Genome Length

736864 bp

Protein-coding Genes

617 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
23s rrna (uracil(1939)-c(5))-methyltransferase rlmdEXC29_RS06825Not AvailablePositive462614 - 46393951502.2
mate family efflux transporterEXC29_RS02125Not AvailableNegative463932 - 46560263643.7
signal recognition particle-docking protein ftsyEXC29_RS02130Not AvailablePositive465672 - 46672439009.6
sigma factor-like helix-turn-helix dna-binding proteinEXC29_RS02135Not AvailablePositive466727 - 4669578847.68
ump kinaseEXC29_RS02140Not AvailablePositive467898 - 46862326726.5
ribosome-recycling factorEXC29_RS02145Not AvailablePositive468679 - 46923021024.4
phosphatidate cytidylyltransferaseEXC29_RS02150Not AvailablePositive469296 - 47024936449.7
polc-type dna polymerase iiiEXC29_RS02155Not AvailablePositive470280 - 474650167698.0
hypothetical proteinEXC29_RS06830Not AvailablePositive474859 - 47539520047.3
serine hydroxymethyltransferaseEXC29_RS02165Not AvailablePositive475420 - 47667646808.3

Displaying genes 431 – 440 of 667 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
OsteonecrosisCausesPMC10998140
OsteomyelitisCausesPMC10998140

Displaying health effects 1 – 2 of 2 in total