Metamycoplasma orale strain NCTC10112

Gram-negativePleomorphicNon-motile

Kingdom

Bacillati

Phylum

Mycoplasmatota

Class

Order

Mycoplasmoidales

Family

Metamycoplasmataceae

Genus

Metamycoplasma

Description

Metamycoplasma orale strain NCTC10112 is a pleomorphic, gram-negative bacterium classified as a chemoheterotroph, indicating that it derives energy from organic compounds. This strain is notable for its lack of mobility, as it does not possess flagella despite their presence in the broader Mycoplasma genus. It thrives optimally at 37°C and falls within the mesophilic temperature range. This bacterium has been identified in multiple habitats and is specifically associated with Homo sapiens as its host. Clinically, Metamycoplasma orale strain NCTC10112 is linked to significant health issues, including osteomyelitis and osteonecrosis, which can have serious implications for bone health and recovery. The organism has two replicons, as indicated by its genomic data, with specific accessions NZ_LR214940.1 and NZ_LR214943.1 available for further research. Importantly, Metamycoplasma orale strain NCTC10112 does not undergo sporulation, which may influence its survival and pathogenicity in various environments. Understanding the pathogenic potential of Metamycoplasma orale strain NCTC10112 in the context of human health underscores the importance of continued research on its ecological niche and interactions within human hosts. This bacterium exemplifies the complex relationship between microbial inhabitants and host health, highlighting the need for awareness regarding its potential impact on bone-related diseases.

Taxonomy

KingdomBacillati
PhylumMycoplasmatota
Class/taxonomy?kingdom=Bacillati&level=klass&phylum=Mycoplasmatota
OrderMycoplasmoidales
FamilyMetamycoplasmataceae
GenusMetamycoplasma
SpeciesMetamycoplasma orale
Strainstrain NCTC10112

Profile

Physiology
Gram staining propertiesNegative
ShapePleomorphic
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Metamycoplasma orale strain NCTC10112


Gene Summary

Adenine Count

275890 bp

Thymine Count

274265 bp

Guanine Count

94355 bp

Cytosine Count

92354 bp

Genome Length

736864 bp

Protein-coding Genes

617 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l33EXC29_RS01085Not AvailableNegative225293 - 2254456053.55
cdp-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferaseEXC29_RS06420Not AvailableNegative225519 - 22652038339.2
mhj_0274 family proteinEXC29_RS06425Not AvailableNegative226507 - 22704920949.4
hypothetical proteinEXC29_RS06430Not AvailableNegative227134 - 22865159393.8
dna polymerase iii subunit deltaEXC29_RS01105Not AvailableNegative228667 - 22963537186.0
leucine-rich repeat domain-containing proteinEXC29_RS06435Not AvailableNegative229785 - 23095442990.6
elongation factor gEXC29_RS01115Not AvailableNegative231150 - 23324377877.1
30s ribosomal protein s7EXC29_RS01120Not AvailableNegative233253 - 23372317917.8
30s ribosomal protein s12EXC29_RS01125Not AvailableNegative233752 - 23416815192.8
aaa family atpaseEXC29_RS06440Not AvailableNegative234374 - 237880137371.0

Displaying genes 221 – 230 of 667 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
OsteonecrosisCausesPMC10998140
OsteomyelitisCausesPMC10998140

Displaying health effects 1 – 2 of 2 in total