Metamycoplasma orale strain NCTC10112

Gram-negativePleomorphicNon-motile

Kingdom

Bacillati

Phylum

Mycoplasmatota

Class

Order

Mycoplasmoidales

Family

Metamycoplasmataceae

Genus

Metamycoplasma

Description

Metamycoplasma orale strain NCTC10112 is a pleomorphic, gram-negative bacterium classified as a chemoheterotroph, indicating that it derives energy from organic compounds. This strain is notable for its lack of mobility, as it does not possess flagella despite their presence in the broader Mycoplasma genus. It thrives optimally at 37°C and falls within the mesophilic temperature range. This bacterium has been identified in multiple habitats and is specifically associated with Homo sapiens as its host. Clinically, Metamycoplasma orale strain NCTC10112 is linked to significant health issues, including osteomyelitis and osteonecrosis, which can have serious implications for bone health and recovery. The organism has two replicons, as indicated by its genomic data, with specific accessions NZ_LR214940.1 and NZ_LR214943.1 available for further research. Importantly, Metamycoplasma orale strain NCTC10112 does not undergo sporulation, which may influence its survival and pathogenicity in various environments. Understanding the pathogenic potential of Metamycoplasma orale strain NCTC10112 in the context of human health underscores the importance of continued research on its ecological niche and interactions within human hosts. This bacterium exemplifies the complex relationship between microbial inhabitants and host health, highlighting the need for awareness regarding its potential impact on bone-related diseases.

Taxonomy

KingdomBacillati
PhylumMycoplasmatota
Class/taxonomy?kingdom=Bacillati&level=klass&phylum=Mycoplasmatota
OrderMycoplasmoidales
FamilyMetamycoplasmataceae
GenusMetamycoplasma
SpeciesMetamycoplasma orale
Strainstrain NCTC10112

Profile

Physiology
Gram staining propertiesNegative
ShapePleomorphic
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Metamycoplasma orale strain NCTC10112


Gene Summary

Adenine Count

275890 bp

Thymine Count

274265 bp

Guanine Count

94355 bp

Cytosine Count

92354 bp

Genome Length

736864 bp

Protein-coding Genes

617 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dtmp kinaseEXC29_RS00835Not AvailableNegative182705 - 18334925295.5
toprim domain-containing proteinEXC29_RS00840Not AvailableNegative183339 - 18395023967.2
ybab/ebfc family nucleoid-associated proteinEXC29_RS00845Not AvailableNegative183954 - 18424110719.2
dna polymerase iii subunit gamma/tauEXC29_RS00850Not AvailableNegative184251 - 18625776427.9
hypothetical proteinEXC29_RS00855Not AvailablePositive186493 - 18690316107.4
50s ribosomal protein l32EXC29_RS00860Not AvailableNegative186968 - 1871657553.48
50s ribosomal protein l17EXC29_RS00865Not AvailableNegative187217 - 18758213995.2
dna-directed rna polymerase subunit alphaEXC29_RS00870Not AvailableNegative187585 - 18866740446.1
30s ribosomal protein s11EXC29_RS00875Not AvailableNegative188689 - 18906313362.3
30s ribosomal protein s13EXC29_RS00880Not AvailableNegative189063 - 18943414092.3

Displaying genes 171 – 180 of 667 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
OsteonecrosisCausesPMC10998140
OsteomyelitisCausesPMC10998140

Displaying health effects 1 – 2 of 2 in total