Actinobacillus pleuropneumoniae strain NCTC10976

Actinobacillus pleuropneumoniae strain NCTC10976 is a Gram-negative bacterium that is primarily associated with various host species, including Bos (cattle), Sus scrofa (pigs), and Equus caballus (horses). Its ecological niche is categorized as host-associated, indicating a symbiotic relationship with its hosts, which can lead to significant health effects. This strain is known to cause multiple serious conditions, such as endocarditis, peritonitis, meningitis, arthritis, respiratory infections, septicemia, mastitis, metritis, and porcine pleuropneumonia, as well as stillbirths. Morphologically, A. pleuropneumoniae exhibits a rod shape and is non-motile, with the presence of flagella. It typically forms chains, pairs, or singles when observed under conditions suitable for growth. As a facultative anaerobe, this bacterium can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. The bacterium contains a single replicon and has a characteristic double membrane structure, which is common among Gram-negative organisms. The ability to reside within various host species highlights its ecological adaptability and potential for disease transmission across different animals. The health issues associated with A. pleuropneumoniae underline the importance of monitoring and controlling this pathogen in livestock to mitigate its impact on animal health and agriculture. Access to genetic information, such as accession NZ_LR134515.1, can facilitate further research into its pathogenic mechanisms and interactions with host organisms.