Mannheimia haemolytica strain NCTC10643

Mannheimia haemolytica strain NCTC10643 is a Gram-negative, microaerophilic bacterium characterized by its rod shape. This strain has a single replicon, indicating a streamlined genetic structure. It is known to infect various hosts, including Bos taurus (cattle), Bos (bovines), Ovis aries (sheep), Amphibia, Capra hircus (goats), and Gastrotheca (a genus of frogs). Clinically, M. haemolytica strain NCTC10643 is significant due to its association with bovine respiratory disease (BRD) and bovine respiratory disease complex (BRDC), which are major health concerns in livestock. These conditions can lead to severe economic losses in the agricultural sector, particularly affecting cattle health and productivity. The strain is cataloged under the accession number NZ_LR134495.1, which allows for its identification in genomic databases. Understanding the traits and pathogenic potential of M. haemolytica strain NCTC10643 is crucial for developing effective management strategies for BRD in affected livestock populations. Its presence across multiple host species suggests a broader ecological role in both domestic and wild animal health, emphasizing the need for continued research into its epidemiology and control measures.