Streptococcus mutans strain NCTC10920

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mutans strain NCTC10920 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. It is a facultative anaerobe, meaning it can thrive in both the presence and absence of oxygen, and it has an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. Notably, this strain does not exhibit mobility, as it lacks flagella. This strain has a singular replicon and one membrane, indicating a relatively simple genetic and cellular structure. S. mutans is primarily associated with humans (Homo sapiens) and is notable for its biotic relationship, which is classified as free living. It has been linked to significant health effects, particularly in the context of dental health, being a well-known contributor to dental caries and decay. The presence of S. mutans in the human oral cavity underscores its ecological role in the dental microbiome, where it can metabolize dietary sugars to produce acids that demineralize tooth enamel. This process is central to the development of dental caries, highlighting the importance of microbial balance in oral health. Understanding the characteristics of S. mutans NCTC10920 can inform approaches to manage dental health and prevent decay through targeted interventions in oral hygiene and dietary practices.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mutans
Strainstrain NCTC10920

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mutans strain NCTC10920
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mutans strain NCTC10920 genome assembly, chromosome:

Gene Summary

Adenine Count

620974 bp

Thymine Count

618651 bp

Guanine Count

435148 bp

Cytosine Count

423141 bp

Genome Length

2097914 bp

Protein-coding Genes

1984 genes

Non-Coding Genes

85 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
competence type iv pilus minor pilin comgdEL219_RS01355Not AvailablePositive256749 - 25715615200.4
competence type iv pilus minor pilin comgeEL219_RS01360Not AvailablePositive257128 - 25742111023.7
competence type iv pilus minor pilin comgfEL219_RS01365Not AvailablePositive257408 - 25784216261.5
helix-turn-helix domain-containing proteinEL219_RS01370Not AvailablePositive257820 - 25811611461.1
class i sam-dependent methyltransferaseEL219_RS01375Not AvailablePositive258276 - 25922936239.1
acetate kinaseEL219_RS01380Not AvailablePositive259289 - 26048843644.4
cpbp family intramembrane glutamic endopeptidaseEL219_RS01385Not AvailablePositive260691 - 26136824760.4
pyrroline-5-carboxylate reductaseEL219_RS01390Not AvailableNegative261484 - 26225427246.0
glutamyl aminopeptidaseEL219_RS01395Not AvailableNegative262346 - 26341338850.2
duf4651 domain-containing proteinEL219_RS01400Not AvailablePositive263532 - 26381910887.3

Displaying genes 271 – 280 of 2069 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Dental cariesCausesPMC6060398
Dental cariesCausesPMC10192434
Dental decayCausesPMC3178794
Dental cariesCausesPMC8540521
Dental cariesCausesPMC2863653
Dental cariesCausesPMC3661675
Tooth decayCausesPMC4007547
CariesCausesPMC9165595

Displaying health effects 1 – 8 of 8 in total