Streptococcus mutans strain NCTC10920

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mutans strain NCTC10920 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. It is a facultative anaerobe, meaning it can thrive in both the presence and absence of oxygen, and it has an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. Notably, this strain does not exhibit mobility, as it lacks flagella. This strain has a singular replicon and one membrane, indicating a relatively simple genetic and cellular structure. S. mutans is primarily associated with humans (Homo sapiens) and is notable for its biotic relationship, which is classified as free living. It has been linked to significant health effects, particularly in the context of dental health, being a well-known contributor to dental caries and decay. The presence of S. mutans in the human oral cavity underscores its ecological role in the dental microbiome, where it can metabolize dietary sugars to produce acids that demineralize tooth enamel. This process is central to the development of dental caries, highlighting the importance of microbial balance in oral health. Understanding the characteristics of S. mutans NCTC10920 can inform approaches to manage dental health and prevent decay through targeted interventions in oral hygiene and dietary practices.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mutans
Strainstrain NCTC10920

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mutans strain NCTC10920
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mutans strain NCTC10920 genome assembly, chromosome:

Gene Summary

Adenine Count

620974 bp

Thymine Count

618651 bp

Guanine Count

435148 bp

Cytosine Count

423141 bp

Genome Length

2097914 bp

Protein-coding Genes

1984 genes

Non-Coding Genes

85 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate abc transporter permease subunit pstcEL219_RS06410Not AvailableNegative1251561 - 125249633672.8
phosphate abc transporter substrate-binding protein psts family proteinEL219_RS06415Not AvailableNegative1252592 - 125345530690.7
rsmf rrna methyltransferase first c-terminal domain-containing proteinEL219_RS06420Not AvailableNegative1253548 - 125486148798.5
inositol monophosphatase family proteinEL219_RS06425Not AvailableNegative1254915 - 125564326946.4
upf0223 family proteinEL219_RS06430Not AvailableNegative1255663 - 125594110524.5
spx/mgsr family rna polymerase-binding regulatory proteinEL219_RS06435Not AvailableNegative1255934 - 125634715997.1
bifunctional riboflavin kinase/fad synthetaseEL219_RS06440Not AvailableNegative1256404 - 125732434817.6
trna pseudouridine(55) synthase trubEL219_RS06445Not AvailableNegative1257352 - 125823332374.2
sensor histidine kinaseEL219_RS06450Not AvailableNegative1258338 - 125964849849.5
response regulator transcription factorEL219_RS06455Not AvailableNegative1259649 - 126033826306.0

Displaying genes 1281 – 1290 of 2069 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Dental cariesCausesPMC6060398
Dental cariesCausesPMC10192434
Dental decayCausesPMC3178794
Dental cariesCausesPMC8540521
Dental cariesCausesPMC2863653
Dental cariesCausesPMC3661675
Tooth decayCausesPMC4007547
CariesCausesPMC9165595

Displaying health effects 1 – 8 of 8 in total