Haemophilus influenzae strain NCTC11873

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae strain NCTC11873 is a Gram-negative bacterium known for its rod shape and lack of mobility, as it does not possess flagella. This organism is classified as a facultative anaerobe and thrives optimally at a temperature of 35°C, fitting within the mesophilic temperature range. It has a unique cellular structure characterized by two membranes and a single replicon. This strain is primarily associated with Homo sapiens, where it serves as a free-living microorganism. H. influenzae can cause a range of serious health effects, including bacteremia, pneumonia, meningitis, and sepsis. It is also implicated in necrotizing fasciitis, cellulitis, community-acquired pneumonia, and various respiratory infections, including exacerbations of chronic pulmonary diseases such as chronic obstructive pulmonary disease (COPD). Other conditions linked to this bacterium include otitis media, sinusitis, and epiglottitis, illustrating its role in both invasive and noninvasive diseases. The diverse array of infections attributed to H. influenzae strain NCTC11873 underscores its significant impact on human health, particularly in immunocompromised individuals and those with pre-existing respiratory conditions. Understanding the pathogenic potential of this strain is crucial for developing effective treatment strategies and public health measures to mitigate its associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
Strainstrain NCTC11873

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae strain NCTC11873
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus influenzae strain NCTC11873


Gene Summary

Adenine Count

605244 bp

Thymine Count

600852 bp

Guanine Count

371999 bp

Cytosine Count

370785 bp

Genome Length

1948880 bp

Protein-coding Genes

1727 genes

Non-Coding Genes

235 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail sheathEL230_RS04910Not AvailablePositive969816 - 97094641885.6
Tail tubeEL230_RS04915Not AvailablePositive970950 - 97140216311.3
HolinEL230_RS04920Not AvailablePositive971489 - 9717258724.68
LysEL230_RS04925Not AvailablePositive971718 - 97227820574.7
Orf25EL230_RS04930Not AvailablePositive972263 - 97261013075.9
Hypothetical proteinEL230_RS04935Not AvailablePositive972803 - 97311111339.7
Tail assembly chaperoneEL230_RS09805Not AvailablePositive973120 - 9732906331.54
Putative tail tape measure proteinEL230_RS04940Not AvailablePositive973300 - 97542975735.3
Orf28EL230_RS04945Not AvailablePositive975433 - 97576812650.4
Baseplate j/gp47 family proteinEL230_RS04950Not AvailablePositive975761 - 97693043895.4

Displaying genes 31 – 40 of 1962 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ear infection (otitis media)CausesPMC10964412
Lung infection (pneumonia)CausesPMC10964412
Exacerbations of chronic pulmonary diseases (e.g., chronic obstructive pulmonary disease, protracted bacterial bronchitis, and bronchiectasis)CausesPMC10964412
Ear infectionCausesPMC10964412
Otitis mediaCausesPMC10964412
Lung infectionCausesPMC10964412
PneumoniaCausesPMC10964412
Invasive diseaseCausesPMC10964412
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026

Displaying health effects 1 – 10 of 60 in total