Pasteurella multocida strain NCTC8282

Pasteurella multocida strain NCTC8282 is a Gram-negative bacterium characterized by its rod shape and facultative anaerobic metabolism. It is mesophilic, with an optimal growth temperature of 37°C, and possesses two membranes, a feature typical of Gram-negative bacteria. This strain has a single replicon and lacks mobility, as it does not possess flagella. P. multocida is associated with a variety of hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), Bos taurus (cattle), Ovis aries (sheep), Oryctolagus cuniculus (rabbits), Aves (birds), Canis lupus familiaris (domestic dogs), Felis catus (domestic cats), and Capra hircus (goats). The bacterium is known to cause several health issues across these species, including pneumonia, cellulitis, upper respiratory tract infections, and various forms of septicemia. In particular, it is implicated in diseases such as fowl cholera in birds, bovine respiratory disease complex (BRDC) in cattle, and enzootic pneumonia in small ruminants. The biotic relationship of P. multocida is classified as free-living, suggesting its capability to survive independently in various environments. This adaptability may contribute to its role as a significant pathogen across multiple species, highlighting the ecological importance of monitoring and controlling its spread, particularly in agricultural settings where livestock are present. Understanding the dynamics of P. multocida can inform strategies for disease prevention and management in both human and veterinary medicine.