Escherichia coli strain NCTC9702

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCTC9702 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments, demonstrating a facultative anaerobic metabolism. This strain exhibits mobility, facilitated by the presence of flagella, and has an optimal growth temperature of 37°C, categorizing it as mesophilic. NCTC9702 is characterized by having a single replicon and a double membrane structure. This strain has a diverse range of biotic relationships, as it can be free-living and is associated with multiple hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. This extensive host range suggests a significant ecological adaptability, allowing NCTC9702 to inhabit different biological niches. Clinically, E. coli NCTC9702 is associated with various health issues, particularly in humans. It is known to cause urinary tract infections (UTIs), gastrointestinal infections, and a wide array of other serious conditions, including neonatal meningitis, septicemia, and hemolytic uremic syndrome (HUS). The strain's pathogenicity highlights its potential impact on public health, particularly in relation to foodborne illnesses and infections that can lead to severe complications. In summary, the ecological versatility and pathogenic potential of E. coli strain NCTC9702 underscore its importance in both health and disease, illustrating the complex interactions between microbial inhabitants and their hosts. The strain's ability to thrive in diverse environments and cause significant health challenges emphasizes the need for ongoing surveillance and research into its behavior and effects on various populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCTC9702

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCTC9702
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCTC9702 genome assembly, chromosome: 1.

Gene Summary

Adenine Count

1308570 bp

Thymine Count

1312861 bp

Guanine Count

1341708 bp

Cytosine Count

1334819 bp

Genome Length

5297958 bp

Protein-coding Genes

4800 genes

Non-Coding Genes

509 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-n-acetylglucosamine 1-carboxyvinyltransferaseEL157_RS02910Not AvailablePositive593768 - 59502744820.4
dna-binding transcriptional regulator sfsbEL157_RS02915Not AvailableNegative595075 - 59535310509.6
octaprenyl diphosphate synthaseEL157_RS02920Not AvailableNegative595581 - 59655235219.1
50s ribosomal protein l21EL157_RS02925Not AvailablePositive596811 - 59712211565.0
50s ribosomal protein l27EL157_RS02930Not AvailablePositive597143 - 5974009125.01
dmt family transporterEL157_RS02935Not AvailablePositive597527 - 59849234965.2
obg family gtpase cgtaEL157_RS02940Not AvailablePositive598508 - 59968043230.2
serine-type d-ala-d-ala carboxypeptidaseEL157_RS02945Not AvailableNegative599867 - 60130051801.3
transcription elongation factor greaEL157_RS02950Not AvailablePositive601548 - 60202417642.0
ribosome assembly rna-binding protein yhbyEL157_RS02955Not AvailableNegative602180 - 60247310784.4

Displaying genes 1051 – 1060 of 5309 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total