Kluyvera intermedia strain NCTC12125

Rod

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Kluyvera

Description

Kluyvera intermedia strain NCTC12125 is a Gram-negative, rod-shaped bacterium that is notable for its presence in sewage and soil environments. This organism possesses flagella, which facilitate motility, allowing it to navigate through its habitats effectively. The strain is characterized by having a single replicon, indicating a streamlined genetic structure. K. intermedia is known to be pathogenic in humans, with documented health effects including bacteremia, urinary tract infections, peritonitis, acute cholecystitis, gastroenteritis, pyelonephritis, mediastinitis, soft tissue infections, wound infections, acute pancreatitis, and infected urethrorectal fistula. These diverse health impacts signify its potential as an opportunistic pathogen, particularly in individuals with compromised immune systems. The strain has been cataloged under accession number NZ_LR134138.1, which provides a reference point for further genetic and microbiological studies. The ecological role of Kluyvera intermedia in sewage and soil suggests it may participate in the degradation of organic materials, contributing to nutrient cycling within these environments. However, its association with various serious infections highlights the importance of monitoring its presence and understanding its pathogenic mechanisms, especially in clinical settings where it could pose risks to vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKluyvera
SpeciesKluyvera intermedia
Strainstrain NCTC12125

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Kluyvera intermedia strain NCTC12125
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatsewage; soil
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Kluyvera intermedia strain NCTC12125 chromosome 1, complete

Gene Summary

Adenine Count

1122806 bp

Thymine Count

1124227 bp

Guanine Count

1247750 bp

Cytosine Count

1244273 bp

Genome Length

4739056 bp

Protein-coding Genes

4251 genes

Non-Coding Genes

355 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
laci family dna-binding transcriptional regulatorEL028_RS18065Not AvailableNegative3720954 - 372197037185.7
ompa family lipoproteinEL028_RS18070Not AvailableNegative3722071 - 372273322352.7
cu(+)/ag(+) efflux rnd transporter permease subunit silaEL028_RS18075Not AvailablePositive3722890 - 372521583535.9
n-acetyltransferaseEL028_RS18080Not AvailableNegative3725193 - 372562416843.9
dna-3-methyladenine glycosylase iEL028_RS18085Not AvailableNegative3725602 - 372618321791.0
autotransporter domain-containing proteinEL028_RS18090Not AvailablePositive3726339 - 372704626414.7
mfs transporterEL028_RS18095Not AvailablePositive3727219 - 372842142514.8
kdo(2)-lipid a phosphoethanolamine 7''-transferaseEL028_RS18100Not AvailablePositive3728635 - 373031463793.0
dipeptide abc transporter periplasmic-binding protein dppaEL028_RS18105Not AvailablePositive3731050 - 373265760084.4
dipeptide abc transporter permease dppbEL028_RS18110Not AvailablePositive3732818 - 373383737470.5

Displaying genes 3641 – 3650 of 4606 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GastroenteritisCausesPMC5434259
Acute pancreatitisCausesPMC5434259
BacteremiaCausesPMC5434259
Wound infectionCausesPMC5434259
Urinary tract infectionCausesPMC5434259
PyelonephritisCausesPMC5434259
Acute cholecystitisCausesPMC5434259
PeritonitisCausesPMC5434259
MediastinitisCausesPMC5434259
Infected urethrorectal fistulaCausesPMC5434259

Displaying health effects 1 – 10 of 11 in total