Kluyvera intermedia strain NCTC12125

Rod

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Kluyvera

Description

Kluyvera intermedia strain NCTC12125 is a Gram-negative, rod-shaped bacterium that is notable for its presence in sewage and soil environments. This organism possesses flagella, which facilitate motility, allowing it to navigate through its habitats effectively. The strain is characterized by having a single replicon, indicating a streamlined genetic structure. K. intermedia is known to be pathogenic in humans, with documented health effects including bacteremia, urinary tract infections, peritonitis, acute cholecystitis, gastroenteritis, pyelonephritis, mediastinitis, soft tissue infections, wound infections, acute pancreatitis, and infected urethrorectal fistula. These diverse health impacts signify its potential as an opportunistic pathogen, particularly in individuals with compromised immune systems. The strain has been cataloged under accession number NZ_LR134138.1, which provides a reference point for further genetic and microbiological studies. The ecological role of Kluyvera intermedia in sewage and soil suggests it may participate in the degradation of organic materials, contributing to nutrient cycling within these environments. However, its association with various serious infections highlights the importance of monitoring its presence and understanding its pathogenic mechanisms, especially in clinical settings where it could pose risks to vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKluyvera
SpeciesKluyvera intermedia
Strainstrain NCTC12125

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Kluyvera intermedia strain NCTC12125
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatsewage; soil
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Kluyvera intermedia strain NCTC12125 chromosome 1, complete

Gene Summary

Adenine Count

1122806 bp

Thymine Count

1124227 bp

Guanine Count

1247750 bp

Cytosine Count

1244273 bp

Genome Length

4739056 bp

Protein-coding Genes

4251 genes

Non-Coding Genes

355 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
isovaleryl-coa dehydrogenaseEL028_RS14750Not AvailableNegative3025046 - 302666859903.3
tellurite resistance/c4-dicarboxylate transporter family proteinEL028_RS14755Not AvailableNegative3026750 - 302783840260.6
cu(+)/ag(+) efflux rnd transporter permease subunit silaEL028_RS14760Not AvailableNegative3027889 - 302862126806.2
ribonuclease rEL028_RS14765Not AvailableNegative3028706 - 303122894580.3
nitric oxide-sensing transcriptional repressor nsrrEL028_RS14770Not AvailableNegative3031270 - 303169515696.3
adenylosuccinate synthaseEL028_RS14775Not AvailableNegative3031923 - 303322147216.6
duf2065 domain-containing proteinEL028_RS14780Not AvailableNegative3033323 - 30335207111.24
protease modulator hflcEL028_RS14785Not AvailableNegative3033592 - 303459637421.5
ftsh protease activity modulator hflkEL028_RS14790Not AvailableNegative3034599 - 303586145662.5
ribosome rescue gtpase hflxEL028_RS14795Not AvailableNegative3036019 - 303729948197.9

Displaying genes 2991 – 3000 of 4606 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GastroenteritisCausesPMC5434259
Acute pancreatitisCausesPMC5434259
BacteremiaCausesPMC5434259
Wound infectionCausesPMC5434259
Urinary tract infectionCausesPMC5434259
PyelonephritisCausesPMC5434259
Acute cholecystitisCausesPMC5434259
PeritonitisCausesPMC5434259
MediastinitisCausesPMC5434259
Infected urethrorectal fistulaCausesPMC5434259

Displaying health effects 1 – 10 of 11 in total