Kluyvera intermedia strain NCTC12125

Rod

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Kluyvera

Description

Kluyvera intermedia strain NCTC12125 is a Gram-negative, rod-shaped bacterium that is notable for its presence in sewage and soil environments. This organism possesses flagella, which facilitate motility, allowing it to navigate through its habitats effectively. The strain is characterized by having a single replicon, indicating a streamlined genetic structure. K. intermedia is known to be pathogenic in humans, with documented health effects including bacteremia, urinary tract infections, peritonitis, acute cholecystitis, gastroenteritis, pyelonephritis, mediastinitis, soft tissue infections, wound infections, acute pancreatitis, and infected urethrorectal fistula. These diverse health impacts signify its potential as an opportunistic pathogen, particularly in individuals with compromised immune systems. The strain has been cataloged under accession number NZ_LR134138.1, which provides a reference point for further genetic and microbiological studies. The ecological role of Kluyvera intermedia in sewage and soil suggests it may participate in the degradation of organic materials, contributing to nutrient cycling within these environments. However, its association with various serious infections highlights the importance of monitoring its presence and understanding its pathogenic mechanisms, especially in clinical settings where it could pose risks to vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKluyvera
SpeciesKluyvera intermedia
Strainstrain NCTC12125

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Kluyvera intermedia strain NCTC12125
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatsewage; soil
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Kluyvera intermedia strain NCTC12125 chromosome 1, complete

Gene Summary

Adenine Count

1122806 bp

Thymine Count

1124227 bp

Guanine Count

1247750 bp

Cytosine Count

1244273 bp

Genome Length

4739056 bp

Protein-coding Genes

4251 genes

Non-Coding Genes

355 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
mdr efflux pump acrab transcriptional activator robaEL028_RS13695Not AvailablePositive2810892 - 281176133330.3
2,3-diphosphoglycerate-dependent phosphoglycerate mutase gpmbEL028_RS13700Not AvailableNegative2811758 - 281240523706.2
inosine/xanthosine triphosphataseEL028_RS13705Not AvailablePositive2812458 - 281297318213.6
trp operon repressorEL028_RS13710Not AvailableNegative2813014 - 281333712262.7
murein transglycosylaseEL028_RS13715Not AvailableNegative2813401 - 281533873547.0
energy-dependent translational throttle protein ettaEL028_RS13720Not AvailablePositive2815683 - 281735062226.2
multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase nadrEL028_RS13725Not AvailableNegative2817406 - 281863547085.9
dna repair protein radaEL028_RS13730Not AvailableNegative2818740 - 282012849684.3
phosphoserine phosphataseEL028_RS13735Not AvailableNegative2820140 - 282111135277.9
ytjb family periplasmic proteinEL028_RS13740Not AvailablePositive2821216 - 282185123674.9

Displaying genes 2781 – 2790 of 4606 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GastroenteritisCausesPMC5434259
Acute pancreatitisCausesPMC5434259
BacteremiaCausesPMC5434259
Wound infectionCausesPMC5434259
Urinary tract infectionCausesPMC5434259
PyelonephritisCausesPMC5434259
Acute cholecystitisCausesPMC5434259
PeritonitisCausesPMC5434259
MediastinitisCausesPMC5434259
Infected urethrorectal fistulaCausesPMC5434259

Displaying health effects 1 – 10 of 11 in total