Klebsiella aerogenes strain NCTC10006

Gram-negativeRodFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella aerogenes strain NCTC10006 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This organism is primarily associated with human hosts, specifically Homo sapiens, and is capable of causing significant health issues, including bloodstream infections, secondary bacterial infections, and pelvic abscesses. The strain exhibits mobility due to the presence of flagella and thrives in mesophilic temperature ranges, indicating an optimal growth temperature that aligns with typical human body temperatures. Notably, K. aerogenes NCTC10006 has a complex genetic makeup, characterized by a total of 12 replicons, which may contribute to its adaptability and potential virulence. K. aerogenes is known to have a free-living biotic relationship, allowing it to exist independently in various environments, although its pathogenicity is predominantly observed in clinical settings. The bacterium's ability to survive and multiply in the human host can lead to serious health complications, particularly in immunocompromised individuals. In summary, Klebsiella aerogenes strain NCTC10006 is a significant pathogen in the healthcare context, associated with serious infections in humans. Its adaptability and pathogenic potential underscore the importance of understanding its ecological and biological characteristics, especially in the context of infection control and treatment strategies in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella aerogenes
Strainstrain NCTC10006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Klebsiella aerogenes strain NCTC10006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

1739 bp

Thymine Count

1772 bp

Guanine Count

1322 bp

Cytosine Count

1416 bp

Genome Length

6249 bp

Protein-coding Genes

6 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

12

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chromosomal replication initiator protein dnaaEL067_RS25540Not AvailablePositive54298 - 5569852323.5
dna polymerase iii subunit betaEL067_RS25545Not AvailablePositive55703 - 5680340589.9
dna replication/repair protein recfEL067_RS25550Not AvailablePositive56952 - 5802540499.4
dna topoisomerase (atp-hydrolyzing) subunit bEL067_RS25555Not AvailablePositive58054 - 6046889951.9
sugar-phosphataseEL067_RS25560Not AvailablePositive60671 - 6148329636.7
hypothetical proteinEL067_RS25565Not AvailablePositive61803 - 6281637131.2
bama/tama family outer membrane proteinEL067_RS25570Not AvailablePositive62813 - 6395242471.8
d-galactonate utilization transcriptional regulator dgorEL067_RS25575Not AvailablePositive64186 - 6487526051.0
2-dehydro-3-deoxygalactonokinaseEL067_RS25580Not AvailablePositive64872 - 6575031221.4
2-dehydro-3-deoxy-6-phosphogalactonate aldolaseEL067_RS25585Not AvailablePositive65734 - 6635121496.0

Displaying genes 61 – 70 of 5191 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
Bloodstream infectionsCausesPMC8934286
Secondary bacterial infectionsCausesPMC8934286
Pelvic abscessCausesPMC8984993

Displaying health effects 1 – 5 of 5 in total