Bacillus cereus strain A22

Gram-positiveRodMotileAerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Bacillaceae

Genus

Bacillus

Description

Bacillus cereus strain A22 is a Gram-positive, aerobic, rod-shaped bacterium that typically forms chains and is known for its mobility, facilitated by the presence of flagella. This strain thrives in various habitats and is classified as mesophilic, with an optimal temperature of 25°C. It possesses three replicons and a single membrane, indicating a complex genetic structure. The biotic relationships of Bacillus cereus strain A22 are predominantly free-living, although it has been observed to interact with a wide range of hosts, including Homo sapiens, Gallus gallus, and various invertebrates like Insecta and Nematoda, as well as other Metazoa. The strain is noted for its pathogenicity in humans, causing various health concerns including bacteremia, pneumonia, meningitis, and foodborne illnesses. Specific ailments associated with B. cereus strain A22 include severe systemic multi-organ failure, necrotizing fasciitis, and gastrointestinal infections, often linked to food safety incidents. The broad host range and significant pathogenic potential of Bacillus cereus strain A22 highlight its ecological role as both a saprophyte and a pathogen. Its ability to cause disease in diverse organisms, from mammals to insects, underscores the importance of monitoring this bacterium in both clinical and environmental contexts, particularly regarding food safety and public health. Understanding its distribution and effects can inform strategies for mitigating the risks associated with its pathogenicity.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyBacillaceae
GenusBacillus
SpeciesBacillus cereus
Strainstrain A22

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Bacillus cereus strain A22
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature25
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Bacillus cereus strain A22 chromosome, complete genome.

Gene Summary

Adenine Count

1716438 bp

Thymine Count

1722882 bp

Guanine Count

934885 bp

Cytosine Count

936586 bp

Genome Length

5310791 bp

Protein-coding Genes

5279 genes

Non-Coding Genes

221 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
atp phosphoribosyltransferase regulatory subunitFHP23_RS06985Not AvailablePositive1343610 - 134487248853.8
atp phosphoribosyltransferaseFHP23_RS06990Not AvailablePositive1344848 - 134548323628.1
histidinol dehydrogenaseFHP23_RS06995Not AvailablePositive1345495 - 134678447468.1
imidazoleglycerol-phosphate dehydratase hisbFHP23_RS07000Not AvailablePositive1346784 - 134736821368.3
imidazole glycerol phosphate synthase subunit hishFHP23_RS07005Not AvailablePositive1347369 - 134799823376.6
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomeraseFHP23_RS07010Not AvailablePositive1347971 - 134869025984.9
imidazoleglycerol phosphate synthase cyclase subunitFHP23_RS07015Not AvailablePositive1348684 - 134944226991.5
phosphoribosyl-amp cyclohydrolaseFHP23_RS07020Not AvailablePositive1349439 - 134974411642.9
phosphoribosyl-atp diphosphataseFHP23_RS07025Not AvailablePositive1349755 - 135007812561.2
histidinol phosphate phosphatase domain-containing proteinFHP23_RS07030Not AvailablePositive1350091 - 135110739540.9

Displaying genes 1501 – 1510 of 6038 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Late-onset neonatal sepsisCausesPMC11282708
Neonatal sepsisCausesPMC11282708
Food poisoningCausesPMC11282708
SepsisCausesPMC11282708
MeningitisCausesPMC11282708
PneumoniaCausesPMC11282708
Foodborne illnessesCausesPMC11282708
Severe systemic multi-organ failureCausesPMC11282708
Anthrax-like skin infectionsCausesPMC11282708
Severe neonatal skin infections resembling anthrax-like lesionsCausesPMC11282708

Displaying health effects 1 – 10 of 75 in total