Bifidobacterium longum subsp. infantis strain Bi-26

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis strain Bi-26 is a non-pathogenic, anaerobic bacterium that is part of the gut microbiota in Homo sapiens, particularly in infants. This strain is characterized as gram-positive and exhibits a rod-shaped morphology. The cells typically arrange themselves in clusters, pairs, or singles, reflecting their communal living strategy. As a mesophilic organism, Bifidobacterium longum subsp. infantis Bi-26 thrives optimally at a temperature of 37°C, which aligns with the average human body temperature. The strain has a single membrane and a singular replicon, indicating a relatively simple genetic structure. It lacks mobility, as it does not possess flagella, which is typical for many members of the Bifidobacterium genus. This strain's free-living biotic relationship suggests that, while it resides in the human gut, it does not rely exclusively on a host for survival. Instead, it plays a role in the gastrointestinal ecosystem, contributing to gut health. Bifidobacterium longum subsp. infantis Bi-26 is significant in the context of infant nutrition and health, as it aids in the digestion of human milk oligosaccharides and supports the development of a healthy gut microbiome. This highlights the strain's importance in maintaining the balance of gut microbiota and potentially enhancing immune function in its host. The accession number for this strain is NZ_CP054425.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis strain Bi-26

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis strain Bi-26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain Bi-26 chromosome.

Gene Summary

Adenine Count

528349 bp

Thymine Count

533519 bp

Guanine Count

776343 bp

Cytosine Count

769912 bp

Genome Length

2608223 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
class 1b ribonucleoside-diphosphate reductase subunit betaEE567_RS11360Not AvailableNegative2575481 - 257647337684.0
class 1b ribonucleoside-diphosphate reductase subunit alphaEE567_RS11365Not AvailableNegative2576702 - 257889781536.1
class ib ribonucleoside-diphosphate reductase assembly flavoprotein nrdiEE567_RS11370Not AvailableNegative2579011 - 257946316442.7
glutaredoxin family proteinEE567_RS11375Not AvailableNegative2579460 - 25797269555.29
helix-turn-helix transcriptional regulatorEE567_RS11380Not AvailableNegative2580281 - 258093124042.6
duf3990 domain-containing proteinEE567_RS11385Not AvailableNegative2580915 - 258159525513.2
potassium channel family proteinEE567_RS11390Not AvailablePositive2581788 - 258255528676.3
glycoside hydrolase family 3 n-terminal domain-containing proteinEE567_RS11395Not AvailableNegative2582777 - 258307111491.5
serine/threonine-protein kinaseEE567_RS11400Not AvailablePositive2583445 - 258572478850.7
dsba family proteinEE567_RS11405Not AvailablePositive2585902 - 258687935256.4

Displaying genes 2291 – 2300 of 2318 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.