Bifidobacterium longum subsp. infantis strain Bi-26

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis strain Bi-26 is a non-pathogenic, anaerobic bacterium that is part of the gut microbiota in Homo sapiens, particularly in infants. This strain is characterized as gram-positive and exhibits a rod-shaped morphology. The cells typically arrange themselves in clusters, pairs, or singles, reflecting their communal living strategy. As a mesophilic organism, Bifidobacterium longum subsp. infantis Bi-26 thrives optimally at a temperature of 37°C, which aligns with the average human body temperature. The strain has a single membrane and a singular replicon, indicating a relatively simple genetic structure. It lacks mobility, as it does not possess flagella, which is typical for many members of the Bifidobacterium genus. This strain's free-living biotic relationship suggests that, while it resides in the human gut, it does not rely exclusively on a host for survival. Instead, it plays a role in the gastrointestinal ecosystem, contributing to gut health. Bifidobacterium longum subsp. infantis Bi-26 is significant in the context of infant nutrition and health, as it aids in the digestion of human milk oligosaccharides and supports the development of a healthy gut microbiome. This highlights the strain's importance in maintaining the balance of gut microbiota and potentially enhancing immune function in its host. The accession number for this strain is NZ_CP054425.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis strain Bi-26

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis strain Bi-26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain Bi-26 chromosome.

Gene Summary

Adenine Count

528349 bp

Thymine Count

533519 bp

Guanine Count

776343 bp

Cytosine Count

769912 bp

Genome Length

2608223 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter permeaseEE567_RS08685Not AvailableNegative1905772 - 190673733141.8
abc transporter substrate-binding proteinEE567_RS08690Not AvailableNegative1906868 - 190853260661.0
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase coabcEE567_RS08695Not AvailablePositive1908790 - 191010346091.9
type iii pantothenate kinaseEE567_RS08700Not AvailablePositive1910107 - 191087427820.4
abc transporter substrate-binding proteinEE567_RS08705Not AvailableNegative1910945 - 191236652249.1
is30 family transposaseEE567_RS08710Not AvailableNegative1912448 - 191355442360.5
beta-galactosidaseEE567_RS08715Not AvailableNegative1913711 - 191578677428.4
pseudouridine synthaseEE567_RS08720Not AvailableNegative1915893 - 191662727822.3
glutamine--fructose-6-phosphate transaminase (isomerizing)EE567_RS08725Not AvailableNegative1916671 - 191856368731.8
amino acid abc transporter atp-binding proteinEE567_RS08730Not AvailableNegative1918783 - 191961330046.6

Displaying genes 1751 – 1760 of 2318 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.