Bifidobacterium longum subsp. infantis strain Bi-26

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis strain Bi-26 is a non-pathogenic, anaerobic bacterium that is part of the gut microbiota in Homo sapiens, particularly in infants. This strain is characterized as gram-positive and exhibits a rod-shaped morphology. The cells typically arrange themselves in clusters, pairs, or singles, reflecting their communal living strategy. As a mesophilic organism, Bifidobacterium longum subsp. infantis Bi-26 thrives optimally at a temperature of 37°C, which aligns with the average human body temperature. The strain has a single membrane and a singular replicon, indicating a relatively simple genetic structure. It lacks mobility, as it does not possess flagella, which is typical for many members of the Bifidobacterium genus. This strain's free-living biotic relationship suggests that, while it resides in the human gut, it does not rely exclusively on a host for survival. Instead, it plays a role in the gastrointestinal ecosystem, contributing to gut health. Bifidobacterium longum subsp. infantis Bi-26 is significant in the context of infant nutrition and health, as it aids in the digestion of human milk oligosaccharides and supports the development of a healthy gut microbiome. This highlights the strain's importance in maintaining the balance of gut microbiota and potentially enhancing immune function in its host. The accession number for this strain is NZ_CP054425.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis strain Bi-26

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis strain Bi-26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain Bi-26 chromosome.

Gene Summary

Adenine Count

528349 bp

Thymine Count

533519 bp

Guanine Count

776343 bp

Cytosine Count

769912 bp

Genome Length

2608223 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
30s ribosomal protein s1EE567_RS07645Not AvailableNegative1682730 - 168420554546.1
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolaseEE567_RS07650Not AvailableNegative1684326 - 168520130946.4
metal abc transporter solute-binding protein, zn/mn familyEE567_RS07655Not AvailablePositive1685305 - 168648641022.8
abc transporter atp-binding proteinEE567_RS07660Not AvailablePositive1686658 - 168754831892.3
metal abc transporter permeaseEE567_RS07665Not AvailablePositive1687615 - 168844828592.1
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseEE567_RS07670Not AvailableNegative1688499 - 168902317450.5
card family transcriptional regulatorEE567_RS07675Not AvailableNegative1689132 - 168972521748.1
glycoside hydrolase family 3 n-terminal domain-containing proteinEE567_RS07680Not AvailablePositive1689903 - 169215683907.3
response regulator transcription factorEE567_RS07685Not AvailablePositive1692192 - 169291426282.8
sensor histidine kinaseEE567_RS07690Not AvailablePositive1692914 - 169398739236.9

Displaying genes 1541 – 1550 of 2318 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.