Bifidobacterium longum subsp. infantis strain Bi-26

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis strain Bi-26 is a non-pathogenic, anaerobic bacterium that is part of the gut microbiota in Homo sapiens, particularly in infants. This strain is characterized as gram-positive and exhibits a rod-shaped morphology. The cells typically arrange themselves in clusters, pairs, or singles, reflecting their communal living strategy. As a mesophilic organism, Bifidobacterium longum subsp. infantis Bi-26 thrives optimally at a temperature of 37°C, which aligns with the average human body temperature. The strain has a single membrane and a singular replicon, indicating a relatively simple genetic structure. It lacks mobility, as it does not possess flagella, which is typical for many members of the Bifidobacterium genus. This strain's free-living biotic relationship suggests that, while it resides in the human gut, it does not rely exclusively on a host for survival. Instead, it plays a role in the gastrointestinal ecosystem, contributing to gut health. Bifidobacterium longum subsp. infantis Bi-26 is significant in the context of infant nutrition and health, as it aids in the digestion of human milk oligosaccharides and supports the development of a healthy gut microbiome. This highlights the strain's importance in maintaining the balance of gut microbiota and potentially enhancing immune function in its host. The accession number for this strain is NZ_CP054425.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis strain Bi-26

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis strain Bi-26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain Bi-26 chromosome.

Gene Summary

Adenine Count

528349 bp

Thymine Count

533519 bp

Guanine Count

776343 bp

Cytosine Count

769912 bp

Genome Length

2608223 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctionalEE567_RS06570Not AvailableNegative1445491 - 1448721120083.0
choloylglycine hydrolaseEE567_RS06575Not AvailableNegative1448778 - 144973135156.0
methylenetetrahydrofolate reductaseEE567_RS06580Not AvailableNegative1449865 - 145071931558.4
5-methyltetrahydropteroyltriglutamate-- homocysteine s-methyltransferaseEE567_RS06585Not AvailableNegative1450779 - 145308285334.4
sixa phosphatase family proteinEE567_RS06590Not AvailableNegative1453244 - 145380120359.7
trna (adenine-n1)-methyltransferaseEE567_RS06595Not AvailableNegative1453899 - 145496939936.6
alpha/beta hydrolaseEE567_RS06600Not AvailablePositive1455052 - 145568423182.5
hypothetical proteinEE567_RS06605Not AvailableNegative1455810 - 145619013728.3
phosphoesteraseEE567_RS11715Not AvailablePositive1456399 - 145703123944.9
hypothetical proteinEE567_RS11885Not AvailableNegative1457096 - 14572184436.23

Displaying genes 1321 – 1330 of 2318 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.