Escherichia coli strain CVM N17EC0616

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain CVM N17EC0616 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen levels, and is typically found in host-associated habitats. It is mesophilic, with an optimal growth temperature of 37°C. CVM N17EC0616 has been identified as a pathogen in humans and is associated with a wide range of health effects, particularly in causing urinary tract infections (UTIs), gastrointestinal infections, and septicemia. It can lead to serious conditions such as neonatal meningitis, hemolytic uremic syndrome (HUS), and colibacillosis, among others. The strain has a diverse array of hosts, including various mammals (e.g., Homo sapiens, Bos taurus, Sus scrofa) and non-mammalian species (e.g., Solanum lycopersicum, Apis mellifera), indicating a broad ecological niche. The presence of two replicons and double membranes suggests a complex genetic and structural organization, which may contribute to its adaptability and pathogenic potential. Given its free-living biotic relationship, CVM N17EC0616 can persist in various environments, potentially facilitating transmission between hosts. The pathogenicity of this strain underscores the importance of monitoring E. coli in both clinical and ecological contexts, particularly as it relates to public health and food safety. Its association with significant health complications highlights the need for continued research into prevention and treatment strategies for infections caused by this versatile bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain CVM N17EC0616

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain CVM N17EC0616
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain CVM N17EC0616 chromosome, complete genome.

Gene Summary

Adenine Count

1257187 bp

Thymine Count

1257221 bp

Guanine Count

1282567 bp

Cytosine Count

1278421 bp

Genome Length

5075396 bp

Protein-coding Genes

4504 genes

Non-Coding Genes

344 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
iron-siderophore abc transporter substrate-binding proteinD9G11_RS03645Not AvailablePositive762050 - 76299734521.7
murr/rpir family transcriptional regulatorD9G11_RS03650Not AvailablePositive762994 - 76388132220.4
putative quinol monooxygenaseD9G11_RS03655Not AvailableNegative763926 - 76424011533.1
nadph:quinone oxidoreductase mdabD9G11_RS03660Not AvailableNegative764271 - 76485221892.1
duf2645 family proteinD9G11_RS03665Not AvailablePositive765210 - 76554213242.7
quorum sensing histidine kinase qsecD9G11_RS03670Not AvailableNegative765588 - 76693750281.6
quorum sensing response regulator transcription factor qsebD9G11_RS03675Not AvailableNegative766934 - 76759324675.1
ob fold stress tolerance protein ygiwD9G11_RS03680Not AvailablePositive767745 - 76813714011.5
arac family transcriptional regulatorD9G11_RS03685Not AvailablePositive768190 - 76867217860.3
abc transporter substrate-binding proteinD9G11_RS03690Not AvailablePositive768781 - 77038860667.1

Displaying genes 971 – 980 of 5037 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total